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- Bf3a3c0cf95c19d86c64ed1685f52a460 NCIT_P378 "NCI" @default.
- Bf3a3c0cf95c19d86c64ed1685f52a460 type Axiom @default.
- Bf3a3c0cf95c19d86c64ed1685f52a460 annotatedProperty IAO_0000115 @default.
- Bf3a3c0cf95c19d86c64ed1685f52a460 annotatedSource NCIT_C14114 @default.
- Bf3a3c0cf95c19d86c64ed1685f52a460 annotatedTarget "Many calcium-binding proteins belong to the same evolutionary family and share a type of calcium-binding domain known as the EF-hand. This type of domain consists of a twelve residue loop flanked on both side by a twelve residue alpha-helical domain. In an EF-hand loop the calcium ion is coordinated in a pentagonal bipyramidal configuration. The six residues involved in the binding are in positions 1, 3, 5, 7, 9 and 12; these residues are denoted by X, Y, Z, -Y, -X and -Z. The invariant Glu or Asp at position 12 provides two oxygens for liganding Ca (bidentate ligand). (From InterPro IPR002048)" @default.