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- Bf5369157e96afb1361e4c10fcf76f8af NCIT_P378 "NCI" @default.
- Bf5369157e96afb1361e4c10fcf76f8af type Axiom @default.
- Bf5369157e96afb1361e4c10fcf76f8af annotatedProperty IAO_0000115 @default.
- Bf5369157e96afb1361e4c10fcf76f8af annotatedSource NCIT_C1862 @default.
- Bf5369157e96afb1361e4c10fcf76f8af annotatedTarget "A poorly adsorbed analog of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. (NCI)" @default.