Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bf562ab26184761dc2b8670216efa9fcb> ?p ?o ?g. }
Showing items 1 to 6 of
6
with 100 items per page.
- Bf562ab26184761dc2b8670216efa9fcb NCIT_P378 "NCI" @default.
- Bf562ab26184761dc2b8670216efa9fcb NCIT_P381 "www.mshri.on.ca/pawson" @default.
- Bf562ab26184761dc2b8670216efa9fcb type Axiom @default.
- Bf562ab26184761dc2b8670216efa9fcb annotatedProperty IAO_0000115 @default.
- Bf562ab26184761dc2b8670216efa9fcb annotatedSource NCIT_C14103 @default.
- Bf562ab26184761dc2b8670216efa9fcb annotatedTarget "The F-box consists of three helices. The H1 helix packs orthogonally with the H2-H3 antiparallel pair. The F-box domain is a 42-48 amino acid conserved domain found at the N-terminus of F-box proteins. F-box proteins act as adaptor components of the modular E3 ubiquitin ligase SCF complex that functions in phosphorylation mediated ubiquitination. The F-box domain mediates interaction with Skp1, which links F-box proteins to a core ubiquitin-ligase complex composed of Rbx1, cdc53/Cul1 and the E2 conjugating enzyme cdc34. The C-terminal region of F-box proteins are also composed of various modular domain that interact with target substrates, often in a phosphorylation dependant manner." @default.