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- Bf80bca92ac5d5115f78cc6f216afd069 NCIT_P378 "NCI" @default.
- Bf80bca92ac5d5115f78cc6f216afd069 type Axiom @default.
- Bf80bca92ac5d5115f78cc6f216afd069 annotatedProperty IAO_0000115 @default.
- Bf80bca92ac5d5115f78cc6f216afd069 annotatedSource NCIT_C1049 @default.
- Bf80bca92ac5d5115f78cc6f216afd069 annotatedTarget "A glucose-linked chloroethylnitrosourea with potential antineoplastic activity. Chlorozotocin alkylates DNA and proteins, induces the formation of interstrand DNA and DNA-protein crosslinks, and causes DNA strand breakage, thereby damaging DNA and resulting in cell death. This agent has been shown to exhibit antitumor and immunomodulatory effects in cell lines and animal models. Chlorozotocin is a mutagen and is less myelotoxic than other nitrosoureas. (NCI04)" @default.