Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bf85d44ff9de3300f5f4a053050a34aa6> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Bf85d44ff9de3300f5f4a053050a34aa6 NCIT_P378 "NCI" @default.
- Bf85d44ff9de3300f5f4a053050a34aa6 type Axiom @default.
- Bf85d44ff9de3300f5f4a053050a34aa6 annotatedProperty IAO_0000115 @default.
- Bf85d44ff9de3300f5f4a053050a34aa6 annotatedSource NCIT_C111895 @default.
- Bf85d44ff9de3300f5f4a053050a34aa6 annotatedTarget "An orally bioavailable, dual kinase inhibitor of the epidermal growth factor receptor (EGFR or HER-1) and the human epidermal growth factor receptor 2 (ErbB2 or HER-2), with potential antineoplastic activity. Upon oral administration, pyrotinib binds to and inhibits both EGFR and HER2, which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumor cells. EGFR and HER2 are receptor tyrosine kinases that are upregulated in various tumor cell types and play major roles in tumor cell proliferation and tumor vascularization." @default.