Matches in Ubergraph for { <https://frink.apps.renci.org/.well-known/genid/Bf8a7680c1a5bad1dbe359886b18c287b> ?p ?o ?g. }
Showing items 1 to 5 of
5
with 100 items per page.
- Bf8a7680c1a5bad1dbe359886b18c287b NCIT_P378 "NCI" @default.
- Bf8a7680c1a5bad1dbe359886b18c287b type Axiom @default.
- Bf8a7680c1a5bad1dbe359886b18c287b annotatedProperty IAO_0000115 @default.
- Bf8a7680c1a5bad1dbe359886b18c287b annotatedSource NCIT_C95896 @default.
- Bf8a7680c1a5bad1dbe359886b18c287b annotatedTarget "An orally available small molecule dual inhibitor targeting human vascular endothelial growth factor receptors (VEGFRs) and platelet-derived growth factor receptors (PDGFRs) with antiangiogenic and antineoplastic activities. Vorolanib inhibits all isoforms of VEGFR and PDGFR, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Both VEGFRs and PDGFRs are receptor tyrosine kinases that may be upregulated in various tumor cell types. Vorolanib has been shown to reduce tissue toxicity by 95 percent compared with first-generation kinase inhibitors." @default.