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- Bf8b33384e6d631f0241394bc5619185c NCIT_P378 "NCI" @default.
- Bf8b33384e6d631f0241394bc5619185c type Axiom @default.
- Bf8b33384e6d631f0241394bc5619185c annotatedProperty IAO_0000115 @default.
- Bf8b33384e6d631f0241394bc5619185c annotatedSource NCIT_C17741 @default.
- Bf8b33384e6d631f0241394bc5619185c annotatedTarget "A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products. The damage to biological tissues is caused by superoxide and other free radicals generated by many factors, including exposure to alcohol, medications, trauma, cold, toxins, and radiation or by antimicrobial cellular immunity, metabolic abnormality, or "normal" aging; not synonymous with hypoxia or hyperoxia. Oxidative stress promotes a range of degenerative disorders, including cancer, diabetes, premature aging, Alzheimer's, and many others." @default.