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- Bf8ee0a422a1eac5bbebf51b28d582742 NCIT_P378 "NCI" @default.
- Bf8ee0a422a1eac5bbebf51b28d582742 type Axiom @default.
- Bf8ee0a422a1eac5bbebf51b28d582742 annotatedProperty IAO_0000115 @default.
- Bf8ee0a422a1eac5bbebf51b28d582742 annotatedSource NCIT_C47610 @default.
- Bf8ee0a422a1eac5bbebf51b28d582742 annotatedTarget "The hippurate salt form of methenamine, a prodrug and inactive weak base that slowly hydrolyzes in acidic urine to ammonia and the effective, urinary tract antiseptic formaldehyde. Formaldehyde probably exerts its antibacterial effect by denaturation of protein. Depending on the urinary concentrations, formaldehyde is either bactericidal or bacteriostatic. Formaldehyde urinary concentrations are dependent on urine pH, volume, and flow rate. Formaldehyde acts as an antibacterial agent against gram-positive and gram-negative organisms." @default.