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- Bf8eef758178b72e9abfed388933e42d0 NCIT_P378 "NCI" @default.
- Bf8eef758178b72e9abfed388933e42d0 type Axiom @default.
- Bf8eef758178b72e9abfed388933e42d0 annotatedProperty IAO_0000115 @default.
- Bf8eef758178b72e9abfed388933e42d0 annotatedSource NCIT_C83967 @default.
- Bf8eef758178b72e9abfed388933e42d0 annotatedTarget "A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, moexipril is hydrolyzed into its active form moexiprilat, which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilation. It also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis." @default.