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- Bf93cb9affde6b013efa00d9199424782 NCIT_P378 "NCI" @default.
- Bf93cb9affde6b013efa00d9199424782 type Axiom @default.
- Bf93cb9affde6b013efa00d9199424782 annotatedProperty IAO_0000115 @default.
- Bf93cb9affde6b013efa00d9199424782 annotatedSource NCIT_C1350 @default.
- Bf93cb9affde6b013efa00d9199424782 annotatedTarget "A thiopurine nucleoside derivative with antineoplastic activity. After conversion to the triphosphate, beta-thioguanine deoxyriboside is incorporated into DNA, resulting in inhibition of DNA replication. This agent is cytotoxic against leukemia cell lines and has demonstrated some activity against leukemia cells in vivo. Beta-thioguanine deoxyriboside demonstrates antineoplastic activity against 6-thioguanine-resistant tumor cells. (NCI04)" @default.