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- Bfa44c06704fb81636b89d16c6c7c6bd3 NCIT_P378 "NCI" @default.
- Bfa44c06704fb81636b89d16c6c7c6bd3 type Axiom @default.
- Bfa44c06704fb81636b89d16c6c7c6bd3 annotatedProperty IAO_0000115 @default.
- Bfa44c06704fb81636b89d16c6c7c6bd3 annotatedSource NCIT_C665 @default.
- Bfa44c06704fb81636b89d16c6c7c6bd3 annotatedTarget "The hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin." @default.