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- Bfc1c9af718687ff665d6004897f129f4 NCIT_P378 "NCI" @default.
- Bfc1c9af718687ff665d6004897f129f4 type Axiom @default.
- Bfc1c9af718687ff665d6004897f129f4 annotatedProperty IAO_0000115 @default.
- Bfc1c9af718687ff665d6004897f129f4 annotatedSource NCIT_C2686 @default.
- Bfc1c9af718687ff665d6004897f129f4 annotatedTarget "A cancer vaccine adjuvant consisting of a recombinant fowlpox virus encoding human granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF binds to specific cell surface receptors on various immuno-hematopoietic cell types, enhancing their proliferation and differentiation and stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Administration of recombinant fowlpox GM-CSF vaccine adjuvant may induce an immune response against tumor cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." @default.