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- Bfdba2e03c429654ea22e94400ba9422d NCIT_P378 "NCI" @default.
- Bfdba2e03c429654ea22e94400ba9422d type Axiom @default.
- Bfdba2e03c429654ea22e94400ba9422d annotatedProperty IAO_0000115 @default.
- Bfdba2e03c429654ea22e94400ba9422d annotatedSource NCIT_C103820 @default.
- Bfdba2e03c429654ea22e94400ba9422d annotatedTarget "A fully human monoclonal antibody against killer-cell immunoglobulin-like receptors (KIR), with potential antineoplastic activity. Upon administration, lirilumab binds to KIR, thereby preventing the binding of KIR ligands to KIR on natural killer (NK) cells. By blocking these inhibitory receptors, NK cells become activated and attack cancer cells leading to tumor cell death. KIR, a member of the immunoglobulin superfamily, is expressed on the surface of NK cells." @default.