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- Bfe21a1014ddac8cff031a6828af31b48 NCIT_P378 "NCI" @default.
- Bfe21a1014ddac8cff031a6828af31b48 type Axiom @default.
- Bfe21a1014ddac8cff031a6828af31b48 annotatedProperty IAO_0000115 @default.
- Bfe21a1014ddac8cff031a6828af31b48 annotatedSource NCIT_C107555 @default.
- Bfe21a1014ddac8cff031a6828af31b48 annotatedTarget "An active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potential cardiotonic and antineoplastic activity. Although the mechanism of action of bufalin is still under investigation, this agent is a specific Na+/K+-ATPase inhibitor and can induce apoptosis in cancer cell lines through the activation of the transcription factor AP-1 via a mitogen activated protein kinase (MAPK) pathway." @default.