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• W1001464320 abstract "Terahertz (THz) radiation lies between the microwave and infrared regions of theelectromagnetic spectrum. THz radiation excites intermolecular interactions and isnon-ionising making it a viable tool for medical imaging. This thesis describes the developmentand validation of spectroscopic methods for diagnosis of tissue pathologiesat THz wavelengths. Theoretical techniques were developed to determine the originof the contrast seen in THz images of biological tissue. Specific biological tissuesinvestigated in this thesis were colonic tissues with the aim of determining the originof contrast between healthy and diseased tissue in THz images.This thesis investigates the interaction of THz radiation with matter using simpletissue phantoms made from five biologically relevant materials: water, methanol, lipid,sucrose and gelatin. Phantoms are designed to imitate the spectroscopic properties oftissue at specific wavelengths where physical properties of the phantom, such as concentrationand homogeneity, can be accurately controlled. The frequency-dependentabsorption coefficients, refractive indices and Debye relaxation times of the purecompounds were measured and used as prior knowledge in the different theoreticalmethods for the determination of concentration. Three concentration analysis methodswere investigated, a) linear spectral decomposition, b) spectrally averaged dielectriccoefficient method and c) the Debye relaxation coefficient method. These methodswere validated on phantoms by determining the concentrations of the phantom chromophoresand comparing to the known composition. Two-component phantoms weremade comprising water with methanol, lipid, sucrose or gelatin. Two different three-componentphantoms were created; one with water, methanol and sucrose and a secondwith water, gelatin and lipid. The accuracy and resolution of each method was determinedto assess the potential of each method as a tool for medical diagnosis at THzwavelengths. Finally, the spectroscopic methods were applied to measurements of ex-vivocolon tissues containing cancerous and dysplastic regions. Statistical analysis ofthe reflected time-domain waveforms demonstrated good distinction between healthyand diseased tissues with an estimated sensitivity of 89.2% and specificity of 78.3%." @default.
• W1001464320 created "2016-06-24" @default.
• W1001464320 creator A5056090807 @default.
• W1001464320 date "2009-08-01" @default.
• W1001464320 modified "2023-09-23" @default.
• W1001464320 title "Spectroscopic methods for medical diagnosis at terahertz wavelengths" @default.
• W1001464320 cites W1166867742 @default.
• W1001464320 cites W1517603868 @default.
• W1001464320 cites W1524441647 @default.
• W1001464320 cites W1572232060 @default.
• W1001464320 cites W1591343048 @default.
• W1001464320 cites W1597864587 @default.
• W1001464320 cites W1604480167 @default.
• W1001464320 cites W1846196538 @default.
• W1001464320 cites W1857039622 @default.
• W1001464320 cites W1963977037 @default.
• W1001464320 cites W1965721949 @default.
• W1001464320 cites W1966114483 @default.
• W1001464320 cites W1968407616 @default.
• W1001464320 cites W1969085693 @default.
• W1001464320 cites W1972432506 @default.
• W1001464320 cites W1972602622 @default.
• W1001464320 cites W1972670671 @default.
• W1001464320 cites W1974466641 @default.
• W1001464320 cites W1974559924 @default.
• W1001464320 cites W1974611569 @default.
• W1001464320 cites W1975763772 @default.
• W1001464320 cites W1976222780 @default.
• W1001464320 cites W1976729937 @default.
• W1001464320 cites W1980479669 @default.
• W1001464320 cites W1980590383 @default.
• W1001464320 cites W1980989869 @default.
• W1001464320 cites W1981906521 @default.
• W1001464320 cites W1982278351 @default.
• W1001464320 cites W1983493375 @default.
• W1001464320 cites W1984225869 @default.
• W1001464320 cites W1985741844 @default.
• W1001464320 cites W1988754946 @default.
• W1001464320 cites W1990862877 @default.
• W1001464320 cites W1993202788 @default.
• W1001464320 cites W1995933153 @default.
• W1001464320 cites W1996554297 @default.
• W1001464320 cites W1996617052 @default.
• W1001464320 cites W1997310186 @default.
• W1001464320 cites W1997607952 @default.
• W1001464320 cites W1997943901 @default.
• W1001464320 cites W1999050830 @default.
• W1001464320 cites W1999261029 @default.
• W1001464320 cites W1999609902 @default.
• W1001464320 cites W2000480454 @default.
• W1001464320 cites W2002538165 @default.
• W1001464320 cites W2003003096 @default.
• W1001464320 cites W2003279408 @default.
• W1001464320 cites W2003809548 @default.
• W1001464320 cites W2004614720 @default.
• W1001464320 cites W2004640019 @default.
• W1001464320 cites W2005005853 @default.
• W1001464320 cites W2005420127 @default.
• W1001464320 cites W2005812776 @default.
• W1001464320 cites W2009062239 @default.
• W1001464320 cites W2009803450 @default.
• W1001464320 cites W2011469586 @default.
• W1001464320 cites W2012996960 @default.
• W1001464320 cites W2013368541 @default.
• W1001464320 cites W2016693266 @default.
• W1001464320 cites W2016716123 @default.
• W1001464320 cites W2017559046 @default.
• W1001464320 cites W2017668600 @default.
• W1001464320 cites W2017735061 @default.
• W1001464320 cites W2018612746 @default.
• W1001464320 cites W2018908649 @default.
• W1001464320 cites W2019436076 @default.
• W1001464320 cites W2020805108 @default.
• W1001464320 cites W2021381162 @default.
• W1001464320 cites W2024818396 @default.
• W1001464320 cites W2025136169 @default.
• W1001464320 cites W2026039351 @default.
• W1001464320 cites W2026791416 @default.
• W1001464320 cites W2026927223 @default.
• W1001464320 cites W2029049410 @default.
• W1001464320 cites W2032323900 @default.
• W1001464320 cites W2032700305 @default.
• W1001464320 cites W2033705563 @default.
• W1001464320 cites W2034488429 @default.
• W1001464320 cites W2035652400 @default.
• W1001464320 cites W2036363327 @default.
• W1001464320 cites W2036516535 @default.
• W1001464320 cites W2036902939 @default.
• W1001464320 cites W2037116962 @default.
• W1001464320 cites W2037504411 @default.
• W1001464320 cites W2037913860 @default.
• W1001464320 cites W2037932750 @default.
• W1001464320 cites W2038048798 @default.
• W1001464320 cites W2039556342 @default.
• W1001464320 cites W2040672961 @default.
• W1001464320 cites W2041015291 @default.
• W1001464320 cites W2041996106 @default.
• W1001464320 cites W2044176089 @default.
• W1001464320 cites W2045219490 @default.
• W1001464320 cites W2047330711 @default.

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