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- W100215172 abstract "Publisher Summary This chapter explains the persistence of viral infection in the presence of immunity. A large number of host determinants may contribute to the persistence of viral infection and the production of lesions. Such host factors include age, genetic factors, and the degree of maturity and competence of the immunologic system, the cell types infected by the virus, and the presence of underlying diseases. Important viral determinants include the method by which the virus spreads, the antigenicity of the virus, the physical form of the virus, formation of defective or partially defective viral particles, and occasionally direct effects of the virus on the immune system. The overall host genetic contribution to the development of persistent viral infections remains to be ascertained. The genetic properties of the viruses may be extremely important determinants in the development of persistent infections. The outcome of viral infection appears to be a complex interplay of both viral and host factors in which the host immune response is of major importance. Such host immune responses may be beneficial in preventing, terminating, or limiting disease, or may actually cause the observed disease itself." @default.
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- W100215172 date "1975-01-01" @default.
- W100215172 modified "2023-09-27" @default.
- W100215172 title "PERSISTENCE OF VIRAL INFECTION IN THE PRESENCE OF IMMUNITY" @default.
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- W100215172 doi "https://doi.org/10.1016/b978-0-12-522050-7.50015-0" @default.
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