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• W1002368980 abstract "Brain radiation necrosis is the most serious late adverse event that occurs after 6 months following radiation therapy. Effective treatment for this irreversible brain necrosis has not been established yet. This study tries to establish brain radiation necrosis mouse model using proton or helium beam. The right cerebral hemispheres of C57BL/6J mouse brains were irradiated at doses of 40, 50, 60 Gy with charged particles. In 60 Gy group, brain necrosis that recapitulates human disease was detected after 8 months." @default.
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• W1002368980 date "2015-12-01" @default.
• W1002368980 modified "2023-10-16" @default.
• W1002368980 title "Localized radiation necrosis model in mouse brain using proton ion beams" @default.
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• W1002368980 doi "https://doi.org/10.1016/j.apradiso.2015.07.032" @default.
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