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- W100274642 abstract "This chapter discusses a study to examine the effect of extraneuronal acetylcholine (ACh) on the rate of ACh release from the auerbach plexus of guinea pig ileum. The aim of the present study was to clarify whether the change in the ACh level during cholinesterase inhibition can influence the ACh release. The isolated longitudinal strip of the guinea pig ileum was prepared and suspended in an organ bath of 1.5 ml. To change the extraneuronal concentration of Ach, the organ bath was superfused by eserinized Krebs solution at different rates. Five min effluents were collected and its ACh concentration was determined on guinea pig ileum. Field stimulation was continuously applied during the collection period. At lower superfusion speed, the ACh concentration was high, while the amount of ACh released was low. When the perfusion rate was changed to a higher value, the ACh concentration of the effluent did not decrease to the same extent as the perfusion rate was increased; thus, the release of Ach was enhanced." @default.
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- W100274642 date "1980-01-01" @default.
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- W100274642 title "THE EFFECT OF EXTRANEURONAL ACETYLCHOLINE (ACh) ON THE RATE OF ACh RELEASE FROM THE AUERBACH PLEXUS OF GUINEA PIG ILEUM" @default.
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- W100274642 doi "https://doi.org/10.1016/b978-0-08-025921-5.50012-6" @default.
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