Matches in SemOpenAlex for { <https://semopenalex.org/work/W100322557> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W100322557 endingPage "14" @default.
- W100322557 startingPage "508" @default.
- W100322557 abstract "To determine the role of polymorphisms of genes regulating glutathione S-transferase (GST) and its plasma GST activity in the pathogenesis of chronic obstructive pulmonary disease (COPD).Case-control study.One hundred and sixty-three patients with stable COPD from several community or regional hospitals were matched for age and pack-years smoked with the same number of health controls from the general population. Each participant underwent an interview-based respiratory and smoking questionnaire, lung function testing and gave a blood sample. Genotyping was carried out using a polymerase chain reaction-based method for polymorphisms of glutathione S-transferase theta 1 (GSTT1), glutathione S-transferase mu 1 (GSTM1) and glutathione S-transferase P 1 (GSTP1) genes. Plasma GST activity was measured using the spectrofluorometric method.There were no significant differences in the distribution of various genotypes of polymorphisms of GSTT1, GSTM1 and GSTP1 between COPD patients and healthy controls. GST activity was significantly higher in patients compared with controls, irrespective of their different genotypes, and was not different between patients with different levels of airflow obstruction.Polymorphisms of GSTT1, GSTM1 and GSTP1 genes are unlikely to be involved in the pathogenesis of COPD in Chinese in Hong Kong and Southern China." @default.
- W100322557 created "2016-06-24" @default.
- W100322557 creator A5000702640 @default.
- W100322557 creator A5010496321 @default.
- W100322557 creator A5025515587 @default.
- W100322557 creator A5036181062 @default.
- W100322557 creator A5042455317 @default.
- W100322557 creator A5049030188 @default.
- W100322557 creator A5077589810 @default.
- W100322557 creator A5082481662 @default.
- W100322557 creator A5089082457 @default.
- W100322557 date "2007-05-01" @default.
- W100322557 modified "2023-10-01" @default.
- W100322557 title "Polymorphisms of glutathione S-transferase genes and functional activity in smokers with or without COPD." @default.
- W100322557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17439673" @default.
- W100322557 hasPublicationYear "2007" @default.
- W100322557 type Work @default.
- W100322557 sameAs 100322557 @default.
- W100322557 citedByCount "9" @default.
- W100322557 countsByYear W1003225572012 @default.
- W100322557 countsByYear W1003225572013 @default.
- W100322557 countsByYear W1003225572014 @default.
- W100322557 countsByYear W1003225572015 @default.
- W100322557 countsByYear W1003225572023 @default.
- W100322557 crossrefType "journal-article" @default.
- W100322557 hasAuthorship W100322557A5000702640 @default.
- W100322557 hasAuthorship W100322557A5010496321 @default.
- W100322557 hasAuthorship W100322557A5025515587 @default.
- W100322557 hasAuthorship W100322557A5036181062 @default.
- W100322557 hasAuthorship W100322557A5042455317 @default.
- W100322557 hasAuthorship W100322557A5049030188 @default.
- W100322557 hasAuthorship W100322557A5077589810 @default.
- W100322557 hasAuthorship W100322557A5082481662 @default.
- W100322557 hasAuthorship W100322557A5089082457 @default.
- W100322557 hasConcept C104317684 @default.
- W100322557 hasConcept C126322002 @default.
- W100322557 hasConcept C135763542 @default.
- W100322557 hasConcept C153911025 @default.
- W100322557 hasConcept C181199279 @default.
- W100322557 hasConcept C2776178081 @default.
- W100322557 hasConcept C2776907368 @default.
- W100322557 hasConcept C2777714996 @default.
- W100322557 hasConcept C2780122483 @default.
- W100322557 hasConcept C29456083 @default.
- W100322557 hasConcept C2983914783 @default.
- W100322557 hasConcept C3019047270 @default.
- W100322557 hasConcept C538909803 @default.
- W100322557 hasConcept C54355233 @default.
- W100322557 hasConcept C55493867 @default.
- W100322557 hasConcept C71924100 @default.
- W100322557 hasConcept C86803240 @default.
- W100322557 hasConceptScore W100322557C104317684 @default.
- W100322557 hasConceptScore W100322557C126322002 @default.
- W100322557 hasConceptScore W100322557C135763542 @default.
- W100322557 hasConceptScore W100322557C153911025 @default.
- W100322557 hasConceptScore W100322557C181199279 @default.
- W100322557 hasConceptScore W100322557C2776178081 @default.
- W100322557 hasConceptScore W100322557C2776907368 @default.
- W100322557 hasConceptScore W100322557C2777714996 @default.
- W100322557 hasConceptScore W100322557C2780122483 @default.
- W100322557 hasConceptScore W100322557C29456083 @default.
- W100322557 hasConceptScore W100322557C2983914783 @default.
- W100322557 hasConceptScore W100322557C3019047270 @default.
- W100322557 hasConceptScore W100322557C538909803 @default.
- W100322557 hasConceptScore W100322557C54355233 @default.
- W100322557 hasConceptScore W100322557C55493867 @default.
- W100322557 hasConceptScore W100322557C71924100 @default.
- W100322557 hasConceptScore W100322557C86803240 @default.
- W100322557 hasIssue "5" @default.
- W100322557 hasLocation W1003225571 @default.
- W100322557 hasOpenAccess W100322557 @default.
- W100322557 hasPrimaryLocation W1003225571 @default.
- W100322557 hasRelatedWork W1518785570 @default.
- W100322557 hasRelatedWork W1550247972 @default.
- W100322557 hasRelatedWork W1984721541 @default.
- W100322557 hasRelatedWork W1991490912 @default.
- W100322557 hasRelatedWork W2005446195 @default.
- W100322557 hasRelatedWork W2011756735 @default.
- W100322557 hasRelatedWork W2016275477 @default.
- W100322557 hasRelatedWork W2022821656 @default.
- W100322557 hasRelatedWork W2032510995 @default.
- W100322557 hasRelatedWork W2043954494 @default.
- W100322557 hasRelatedWork W2059410642 @default.
- W100322557 hasRelatedWork W2063352682 @default.
- W100322557 hasRelatedWork W2070862181 @default.
- W100322557 hasRelatedWork W2071223640 @default.
- W100322557 hasRelatedWork W2073112916 @default.
- W100322557 hasRelatedWork W2111901200 @default.
- W100322557 hasRelatedWork W2126783526 @default.
- W100322557 hasRelatedWork W2127951128 @default.
- W100322557 hasRelatedWork W2128806515 @default.
- W100322557 hasRelatedWork W2169483711 @default.
- W100322557 hasVolume "11" @default.
- W100322557 isParatext "false" @default.
- W100322557 isRetracted "false" @default.
- W100322557 magId "100322557" @default.
- W100322557 workType "article" @default.