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- W1003338238 endingPage "181" @default.
- W1003338238 startingPage "123" @default.
- W1003338238 abstract "Isatogens, indolones, and indoxyls form an interrelated redox system. Isatogens and indolones are essentially brightly colored solids that are not formed naturally. In context to synthesis of isatogens, it is noted that they can be prepared by two general methods involving either an intramolecular cyclization or the oxidation of a 2-substituted indole derivative. The chapter analyzes the chemical properties of isatogens that include reactions characteristic of both nitrone and carbonyl groups. With regard to synthesis of indolones, they are reported to form under a variety of conditions. Indolones exhibit both an azomethine and carbonyl group carbon atomwithin the same five-membered ring system. The azomethine group is the more reactive center and readily takes part in reactions typical of that group. The biological properties of isatogens are well-established as compared to indolones. The 2-arylisatogens exhibit significant antimicrobial activity against bacteria, mycoplasma organisms, and the mold Candida albicans. A detailed study of the biochemical effects of 2-phenylisatogen and 2-phenylindolone shows that they both possess a range of action on mitochondria1 respiration." @default.
- W1003338238 created "2016-06-24" @default.
- W1003338238 creator A5004045239 @default.
- W1003338238 creator A5014716492 @default.
- W1003338238 date "1978-01-01" @default.
- W1003338238 modified "2023-09-23" @default.
- W1003338238 title "Isatogens and Indolones" @default.
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