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- W1005890353 abstract "This chapter describes the relation between the steroid metabolism of the host and the genesis of three female cancers—breast cancer, cervical cancer, and endometrial cancer—from the breast and uterus, organs which are known to be subjected to steroidal influences during their developmental stage. Relevant information from epidemiology, endocrinology, and molecular biology is exploited in an effort to extract common principles operating in the production of these three cancers. An attempt was made to investigate comparatively the epidemiological and endocrinological aspects of cancers of the breast, uterine cervix, and endometrium to construct a unifying theory about the genesis of three sex-related neoplasias. Epidemiological studies demonstrated that the risks for breast and cervical cancers were conditioned by specified combinations of three factors—climate, diet, and sex life; an increased risk for breast cancer was associated with a cold climate, a fatty diet, and a delay of, or abstention from, sexual experience, whereas an increased risk for cervical cancer was accompanied by just the reverse in each of the three factors. The chapter presents an evidence to indicate that a patient with endometrial cancer is smaller in stature, less fertile, and more disposed to a fatty diet than a healthy control. It also suggests that the risk of endometrial cancer could be augmented in a stressful environment. In addition, migration studies indicate that the risks for each of the three cancers are subjected to a change through emigration." @default.
- W1005890353 created "2016-06-24" @default.
- W1005890353 creator A5041824293 @default.
- W1005890353 creator A5050477258 @default.
- W1005890353 date "1983-01-01" @default.
- W1005890353 modified "2023-10-16" @default.
- W1005890353 title "Relation Between Steroid Metabolism of the Host and Genesis of Cancers of the Breast, Uterine Cervix, and Endometrium" @default.
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