Matches in SemOpenAlex for { <https://semopenalex.org/work/W1006469021> ?p ?o ?g. }
- W1006469021 endingPage "682" @default.
- W1006469021 startingPage "669" @default.
- W1006469021 abstract "This chapter summarizes the current knowledge about Bacillus ribosomes and translation factors. Much of the information concerning Bacillus ribosome structure and function has been obtained from work with Bacillus stearothermophilus, while most of the genetic analysis has been carried out with B. subtilis. Available information about ribosome structure and genetics in other gram-positive systems are also summarized in this chapter. B. subtilis contains 10 rRNA operons.The sequences of the rrnB and rrnO operons have been determined; they show an organizational pattern identical to that of the E. coli rRNA operons, containing genes for 16S, 23S, and 5S rRNA in that order. Ribosomal-protein gene characterization was initiated by the isolation and mapping of mutations conferring resistance to antibiotics that were known to target the translational machinery. A number of mutants that have alterations in components of the translational apparatus and exhibit defects in sporulation have been identified. These include mutants with altered sensitivity to antibiotics that act on the ribosome and temperature-sensitive mutants that result in spore-minus or spore-conditional phenotypes. In E. coli, sequences in the promoter regions of genes sensitive to the stringent response have been identified, and it has been proposed that (p)ppGpp acts directly as an effector in modulating promoter recognition by RNA polymerase. Expression of a fusion of the B. subtilisrrnO promoter to lacZ was repressed by induction of the stringent response by the addition of serine hydroxamate in wild-type strains but not in a relA-minus mutant." @default.
- W1006469021 created "2016-06-24" @default.
- W1006469021 creator A5078715066 @default.
- W1006469021 date "2014-04-30" @default.
- W1006469021 modified "2023-09-27" @default.
- W1006469021 title "Ribosomal Structure and Genetics" @default.
- W1006469021 cites W1486770091 @default.
- W1006469021 cites W1497265397 @default.
- W1006469021 cites W1504415765 @default.
- W1006469021 cites W1506228827 @default.
- W1006469021 cites W1508779048 @default.
- W1006469021 cites W1510132149 @default.
- W1006469021 cites W1524051883 @default.
- W1006469021 cites W1524605924 @default.
- W1006469021 cites W1531734692 @default.
- W1006469021 cites W1537050699 @default.
- W1006469021 cites W1539957526 @default.
- W1006469021 cites W1542553947 @default.
- W1006469021 cites W1548108521 @default.
- W1006469021 cites W1548706496 @default.
- W1006469021 cites W1550705667 @default.
- W1006469021 cites W1554559408 @default.
- W1006469021 cites W1568834246 @default.
- W1006469021 cites W1588233759 @default.
- W1006469021 cites W1605088984 @default.
- W1006469021 cites W1645883628 @default.
- W1006469021 cites W1675887579 @default.
- W1006469021 cites W1681238892 @default.
- W1006469021 cites W1796287080 @default.
- W1006469021 cites W1821353653 @default.
- W1006469021 cites W1830540498 @default.
- W1006469021 cites W1836723474 @default.
- W1006469021 cites W187631336 @default.
- W1006469021 cites W1939622630 @default.
- W1006469021 cites W1952817825 @default.
- W1006469021 cites W1953600035 @default.
- W1006469021 cites W1962026627 @default.
- W1006469021 cites W1968794294 @default.
- W1006469021 cites W1968812499 @default.
- W1006469021 cites W1970576784 @default.
- W1006469021 cites W1970986513 @default.
- W1006469021 cites W1972413131 @default.
- W1006469021 cites W1972684413 @default.
- W1006469021 cites W1974123101 @default.
- W1006469021 cites W1974168193 @default.
- W1006469021 cites W1979143750 @default.
- W1006469021 cites W1979516815 @default.
- W1006469021 cites W1979672694 @default.
- W1006469021 cites W1980226010 @default.
- W1006469021 cites W1980705976 @default.
- W1006469021 cites W1980881716 @default.
- W1006469021 cites W1981099755 @default.
- W1006469021 cites W1981761311 @default.
- W1006469021 cites W1982501179 @default.
- W1006469021 cites W1984970856 @default.
- W1006469021 cites W1985311973 @default.
- W1006469021 cites W1985320779 @default.
- W1006469021 cites W1986237593 @default.
- W1006469021 cites W1986462990 @default.
- W1006469021 cites W1988405444 @default.
- W1006469021 cites W1988707688 @default.
- W1006469021 cites W1990592635 @default.
- W1006469021 cites W1991591304 @default.
- W1006469021 cites W1991597959 @default.
- W1006469021 cites W1993128416 @default.
- W1006469021 cites W1994501773 @default.
- W1006469021 cites W1995303255 @default.
- W1006469021 cites W1999069644 @default.
- W1006469021 cites W1999161971 @default.
- W1006469021 cites W2001442946 @default.
- W1006469021 cites W2005037829 @default.
- W1006469021 cites W2006178011 @default.
- W1006469021 cites W2008243349 @default.
- W1006469021 cites W2009852466 @default.
- W1006469021 cites W2012457621 @default.
- W1006469021 cites W2016336609 @default.
- W1006469021 cites W2016440873 @default.
- W1006469021 cites W2016785859 @default.
- W1006469021 cites W2018853395 @default.
- W1006469021 cites W2019306978 @default.
- W1006469021 cites W2020134144 @default.
- W1006469021 cites W2020281226 @default.
- W1006469021 cites W2023614501 @default.
- W1006469021 cites W2023826462 @default.
- W1006469021 cites W2024021793 @default.
- W1006469021 cites W2025987130 @default.
- W1006469021 cites W2026654037 @default.
- W1006469021 cites W2026815572 @default.
- W1006469021 cites W2027421592 @default.
- W1006469021 cites W2028778714 @default.
- W1006469021 cites W2031914871 @default.
- W1006469021 cites W2032357327 @default.
- W1006469021 cites W2033680099 @default.
- W1006469021 cites W2033796073 @default.
- W1006469021 cites W2036216377 @default.
- W1006469021 cites W2037467204 @default.
- W1006469021 cites W2037658712 @default.
- W1006469021 cites W2040100288 @default.