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• W1006736825 abstract "This chapter is concerned with the differentiation of neural retina cells. It focuses mainly on the glia cells, and on the role of contact interactions with neurons in the control of their phenotypic characteristics. The main purpose is to bring together findings and interpretations within a framework of a unifying working hypothesis. Studies have been concerned mainly with the characteristics of glia cells in the neural retina (NR) of the chick embryo. There is growing awareness of the importance of glia cells in the development and function of the NR, prompting increased interest in their properties. Among the key functions of glia cells is the regulation of the neuronal extracellular milieu because of their ability to take up and metabolize various transmitters and other products released from nerve terminals and also because they contribute to nerve cells and their immediate microenvironment metabolic and physical conditions essential for normal activity. The chapter reviews published and ongoing work on the developmental programs of two “markers” of definitive glia cells in the NR, the enzymes carbonic anhydrase-C and glutamine synthetase. It describes experiments on modification of definitive glia cells into lens-like cells and proposes that the cell surface and cell interactions play a key role in the expression and stability of Muller glia phenotype." @default.
• W1006736825 created "2016-06-24" @default.
• W1006736825 creator A5026641159 @default.
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• W1006736825 date "1983-01-01" @default.
• W1006736825 modified "2023-10-16" @default.
• W1006736825 title "Chapter 6 Developmental and Experimental Changes in Retinal Glia Cells: Cell Interactions and Control of Phenotype Expression and Stability" @default.
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• W1006736825 doi "https://doi.org/10.1016/s0070-2153(08)60582-7" @default.
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