FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1008355154> ?p ?o ?g. }

• W1008355154 endingPage "267" @default.
• W1008355154 startingPage "243" @default.
• W1008355154 abstract "This chapter discusses the technical aspects of the methods related to treatment of tachykinin (TK) receptors. TKs represent a family of structurally related peptides that share a common C-terminal amino acid sequence, exhibit different rank order of potency according to the tissue investigated, and show some analogy in their biological effects. Mammalian TK are derived from large precursors encoded by two genes, namely, the preprotachykinins A (PPTA) and preprotachykinins B (PPTB) genes. The PPTA large precursors generate substance P (SP) alone or both SP and neurokinin A (NKA), SP and neuropeptide K (NPK), or SP and NPγ through alternative splicing, whereas the PPTB precursors give rise to neurokinin B (NKB) alone. NK1 receptors are characterized by their preferential affinity for SP. NK2 receptors are characterized by their preferential affinity for NKA. NK3 receptors are characterized by their preferential affinity for NKB. Binding studies have demonstrated that TK analogs recognize TK receptors, but the agonist or antagonist properties of these compounds have been demonstrated using biological assays on peripheral isolated organs. It is reported that dog carotid artery, rabbit pulmonary artery, and rat portal vein distinguish responses are mediated by NK1, NK2, and NK3 receptors. However, there is not always a perfect correlation between the relative potencies of TK or analogs in binding studies and those in assays made on these peripheral organs." @default.
• W1008355154 created "2016-06-24" @default.
• W1008355154 creator A5005549596 @default.
• W1008355154 creator A5017991053 @default.
• W1008355154 creator A5039759007 @default.
• W1008355154 creator A5065788023 @default.
• W1008355154 creator A5072867653 @default.
• W1008355154 creator A5078106386 @default.
• W1008355154 date "1991-01-01" @default.
• W1008355154 modified "2023-09-25" @default.
• W1008355154 title "Tachykinin Receptors: Binding and Cellular Activity Assays" @default.
• W1008355154 cites W1542228742 @default.
• W1008355154 cites W1546069046 @default.
• W1008355154 cites W1547131709 @default.
• W1008355154 cites W1573840829 @default.
• W1008355154 cites W1605277785 @default.
• W1008355154 cites W1703900784 @default.
• W1008355154 cites W1889236699 @default.
• W1008355154 cites W1905033678 @default.
• W1008355154 cites W1910204460 @default.
• W1008355154 cites W1944100455 @default.
• W1008355154 cites W1964661171 @default.
• W1008355154 cites W1965035457 @default.
• W1008355154 cites W1967866503 @default.
• W1008355154 cites W1974782548 @default.
• W1008355154 cites W1975646316 @default.
• W1008355154 cites W1980435560 @default.
• W1008355154 cites W1980515277 @default.
• W1008355154 cites W1982211701 @default.
• W1008355154 cites W1982513948 @default.
• W1008355154 cites W1984547809 @default.
• W1008355154 cites W1987699863 @default.
• W1008355154 cites W1988194899 @default.
• W1008355154 cites W1990232471 @default.
• W1008355154 cites W1994820130 @default.
• W1008355154 cites W1994855388 @default.
• W1008355154 cites W1998318672 @default.
• W1008355154 cites W2000285091 @default.
• W1008355154 cites W2002890068 @default.
• W1008355154 cites W2003345023 @default.
• W1008355154 cites W2004877429 @default.
• W1008355154 cites W2004930085 @default.
• W1008355154 cites W2005180392 @default.
• W1008355154 cites W2006548379 @default.
• W1008355154 cites W2006754159 @default.
• W1008355154 cites W2009518509 @default.
• W1008355154 cites W2011972399 @default.
• W1008355154 cites W2015696786 @default.
• W1008355154 cites W2028046140 @default.
• W1008355154 cites W2029153838 @default.
• W1008355154 cites W2029972349 @default.
• W1008355154 cites W2032665330 @default.
• W1008355154 cites W2035170375 @default.
• W1008355154 cites W2042922875 @default.
• W1008355154 cites W2052497630 @default.
• W1008355154 cites W2053366793 @default.
• W1008355154 cites W2056415113 @default.
• W1008355154 cites W2060421948 @default.
• W1008355154 cites W2065379700 @default.
• W1008355154 cites W2067140969 @default.
• W1008355154 cites W2067220196 @default.
• W1008355154 cites W2067562153 @default.
• W1008355154 cites W2069306418 @default.
• W1008355154 cites W2070554934 @default.
• W1008355154 cites W2076100948 @default.
• W1008355154 cites W2079052515 @default.
• W1008355154 cites W2080837506 @default.
• W1008355154 cites W2085020979 @default.
• W1008355154 cites W2086432938 @default.
• W1008355154 cites W2091772002 @default.
• W1008355154 cites W2094876611 @default.
• W1008355154 cites W2095042887 @default.
• W1008355154 cites W2097999910 @default.
• W1008355154 cites W2100766739 @default.
• W1008355154 cites W2134139741 @default.
• W1008355154 cites W2163815564 @default.
• W1008355154 cites W2269968001 @default.
• W1008355154 cites W2496221727 @default.
• W1008355154 cites W2901307123 @default.
• W1008355154 cites W73534840 @default.
• W1008355154 doi "https://doi.org/10.1016/b978-0-12-185259-7.50022-3" @default.
• W1008355154 hasPublicationYear "1991" @default.
• W1008355154 type Work @default.
• W1008355154 sameAs 1008355154 @default.
• W1008355154 citedByCount "15" @default.
• W1008355154 crossrefType "book-chapter" @default.
• W1008355154 hasAuthorship W1008355154A5005549596 @default.
• W1008355154 hasAuthorship W1008355154A5017991053 @default.
• W1008355154 hasAuthorship W1008355154A5039759007 @default.
• W1008355154 hasAuthorship W1008355154A5065788023 @default.
• W1008355154 hasAuthorship W1008355154A5072867653 @default.
• W1008355154 hasAuthorship W1008355154A5078106386 @default.
• W1008355154 hasConcept C118303440 @default.
• W1008355154 hasConcept C126322002 @default.
• W1008355154 hasConcept C135285700 @default.
• W1008355154 hasConcept C153911025 @default.
• W1008355154 hasConcept C170493617 @default.
• W1008355154 hasConcept C185592680 @default.

• next