Matches in SemOpenAlex for { <https://semopenalex.org/work/W1010396112> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W1010396112 abstract "Women have a decreased risk of cardiovascular disease compared to men until after menopause when the risk is similar between men and women. The mechanism for cardioprotective effect is unclear. In order to study the physiological changes which occur in the cardiovascular system of women after menopause it is necessary to identify animal models. One model of post-menopausal physiology is the aged spontaneously hypertensive female rats (SHR). The endocrine and blood pressure changes have been previously reported by Reckelhoff and colleagues. However, the vascular changes have not been characterized. The purpose of this study was to characterize the vascular behavior of coronary arteries in the aged female SHR. Septal coronary arteries were isolated from old and young SHR and studied in a pressure arteriograph. Active and passive diameters were measured over a range of pressures ranging from 10 to 100mmHg. Percent tone was calculated (1-(Dactive-Dpassive)*100%) at each pressure step. At each pressure step from 20–100 mmHg the percent tone was greater in the old SHR (19.8 + 1.5%) compared to young female SHR (7.7+ 0.2%). These results indicate that the aged SHR can be used as a model to study post-menopausal increases in the coronary vascular reactivity. Funded by NIH R15HL097343" @default.
- W1010396112 created "2016-06-24" @default.
- W1010396112 creator A5012314267 @default.
- W1010396112 creator A5014952514 @default.
- W1010396112 creator A5039470169 @default.
- W1010396112 creator A5057881887 @default.
- W1010396112 date "2013-04-01" @default.
- W1010396112 modified "2023-09-26" @default.
- W1010396112 title "Coronary artery reactivity is increased in the aged SHR, a model of postmenopausal vascular physiology." @default.
- W1010396112 doi "https://doi.org/10.1096/fasebj.27.1_supplement.1185.10" @default.
- W1010396112 hasPublicationYear "2013" @default.
- W1010396112 type Work @default.
- W1010396112 sameAs 1010396112 @default.
- W1010396112 citedByCount "0" @default.
- W1010396112 crossrefType "journal-article" @default.
- W1010396112 hasAuthorship W1010396112A5012314267 @default.
- W1010396112 hasAuthorship W1010396112A5014952514 @default.
- W1010396112 hasAuthorship W1010396112A5039470169 @default.
- W1010396112 hasAuthorship W1010396112A5057881887 @default.
- W1010396112 hasConcept C120770815 @default.
- W1010396112 hasConcept C126322002 @default.
- W1010396112 hasConcept C134018914 @default.
- W1010396112 hasConcept C164705383 @default.
- W1010396112 hasConcept C2776820930 @default.
- W1010396112 hasConcept C2777466421 @default.
- W1010396112 hasConcept C2778213512 @default.
- W1010396112 hasConcept C2778562196 @default.
- W1010396112 hasConcept C2778742706 @default.
- W1010396112 hasConcept C2994227525 @default.
- W1010396112 hasConcept C3018603563 @default.
- W1010396112 hasConcept C42407357 @default.
- W1010396112 hasConcept C71924100 @default.
- W1010396112 hasConcept C84393581 @default.
- W1010396112 hasConceptScore W1010396112C120770815 @default.
- W1010396112 hasConceptScore W1010396112C126322002 @default.
- W1010396112 hasConceptScore W1010396112C134018914 @default.
- W1010396112 hasConceptScore W1010396112C164705383 @default.
- W1010396112 hasConceptScore W1010396112C2776820930 @default.
- W1010396112 hasConceptScore W1010396112C2777466421 @default.
- W1010396112 hasConceptScore W1010396112C2778213512 @default.
- W1010396112 hasConceptScore W1010396112C2778562196 @default.
- W1010396112 hasConceptScore W1010396112C2778742706 @default.
- W1010396112 hasConceptScore W1010396112C2994227525 @default.
- W1010396112 hasConceptScore W1010396112C3018603563 @default.
- W1010396112 hasConceptScore W1010396112C42407357 @default.
- W1010396112 hasConceptScore W1010396112C71924100 @default.
- W1010396112 hasConceptScore W1010396112C84393581 @default.
- W1010396112 hasFunder F4320332161 @default.
- W1010396112 hasIssue "S1" @default.
- W1010396112 hasLocation W10103961121 @default.
- W1010396112 hasOpenAccess W1010396112 @default.
- W1010396112 hasPrimaryLocation W10103961121 @default.
- W1010396112 hasRelatedWork W1010396112 @default.
- W1010396112 hasRelatedWork W125405278 @default.
- W1010396112 hasRelatedWork W1966234050 @default.
- W1010396112 hasRelatedWork W1979277576 @default.
- W1010396112 hasRelatedWork W2059716163 @default.
- W1010396112 hasRelatedWork W2111753128 @default.
- W1010396112 hasRelatedWork W2171089442 @default.
- W1010396112 hasRelatedWork W2178782402 @default.
- W1010396112 hasRelatedWork W2351880569 @default.
- W1010396112 hasRelatedWork W6311592 @default.
- W1010396112 hasVolume "27" @default.
- W1010396112 isParatext "false" @default.
- W1010396112 isRetracted "false" @default.
- W1010396112 magId "1010396112" @default.
- W1010396112 workType "article" @default.