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- W1010488329 abstract "This chapter summarizes the knowledge on the behavioral effects of pituitary and adrenal hormones with special attention to the mode, the site and the specificity of their actions on central nervous mechanisms. Pituitary-adrenal system hormones markedly influence adaptive responses of behavioral and autonomic nature. The behavioral effects are present whether a response is motivated by aversive or approach motives. The mode of action of pituitary-adrenal system hormones may be described in terms of an increase or attenuation of the motivational properties of environmental and internal bodily stimuli. The sites of action of hormones are located in the brain stem and the forebrain. Corticosteroids such as cortisone or dexamethasone suppress passive avoidance responses in both aversive vs. aversive and thirst vs. fear conflict situations. Administration of corticotrophin (ACTH)-like peptides reverses the learning deficit of the operated rats. Response performance of hypophysectomized rats can also be restored by supplementary treatment with thyroxine, cortisone and testosterone or by growth hormone." @default.
- W1010488329 created "2016-06-24" @default.
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- W1010488329 date "1973-01-01" @default.
- W1010488329 modified "2023-10-16" @default.
- W1010488329 title "Pituitary-Adrenal Influences on Avoidance and Approach Behavior of the Rat" @default.
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- W1010488329 doi "https://doi.org/10.1016/s0079-6123(08)64096-0" @default.
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