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- W101050558 abstract "We discovered a new anorexigenic protein, nesfatin/nucleobindin-2 (NUCB2), which includes an EF-hand, calcium-binding motif. Nesfatin/NUCB2 is converted to nesfatin-1, which may be a physiologically active form in the body. Centrally and systemically administered nesfatin-1 inhibits appetite and body weight gain in rodents. The mid-segment of nesfatin-1 appears to be important in the inhibition of food intake. Intranasal administration of the mid-segment inhibits appetite. Nesfatin-1 may also be involved in the regulation of gastrointestinal function and insulin secretion. We have summarized the recent progress in the research of nesfatin-1." @default.
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- W101050558 date "2012-11-04" @default.
- W101050558 modified "2023-10-14" @default.
- W101050558 title "Nesfatin-1: Its Role in the Diagnosis and Treatment of Obesity and Some Psychiatric Disorders" @default.
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- W101050558 doi "https://doi.org/10.1007/978-1-62703-230-8_20" @default.
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