Matches in SemOpenAlex for { <https://semopenalex.org/work/W101092216> ?p ?o ?g. }
- W101092216 endingPage "88" @default.
- W101092216 startingPage "78" @default.
- W101092216 abstract "The intratracheal instillation into rabbits of 1-0-octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (AGEPC) or native platelet-activating factor (PAF) was shown to induce a dose-dependent acute pulmonary inflammation characterized by accumulation of macrophages in the alveolar space, degenerative and necrotic changes of alveolar epithelium, and accumulation of polymorphonuclear leukocytes (PMNs) and platelets in the alveolar capillary lumens with degenerative changes of endothelial cells. Infiltration of alveolar septa by inflammatory cells and, in a later stage, pulmonary fibrosis were also observed. Intrabronchial instillation of lysoglyceryl ether phosphorylcholine (lyso-GEPC) produced no inflammatory changes or only mild ones. In comparison with acute inflammation induced by intratracheal instillation of C5a des Arg, which is mainly characterized by the presence of neutrophils, red blood cells, and fibrin in the alveolar space, AGEPC and native PAF seem to induce a more severe accumulation of macrophages in the alveolar space and septa and of platelet and PMNs in the lumens of alveolar capillaries. These results are compatible with the concept that during inflammatory reaction an intraalveolar release of PAF contributes to the development of pulmonary injury." @default.
- W101092216 created "2016-06-24" @default.
- W101092216 creator A5030934019 @default.
- W101092216 creator A5041139639 @default.
- W101092216 creator A5045100634 @default.
- W101092216 creator A5049145562 @default.
- W101092216 creator A5063812862 @default.
- W101092216 creator A5066207319 @default.
- W101092216 creator A5071304634 @default.
- W101092216 date "1983-07-01" @default.
- W101092216 modified "2023-10-10" @default.
- W101092216 title "Acute lung inflammation induced in the rabbit by local instillation of 1-0-octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine or of native platelet-activating factor." @default.
- W101092216 cites W1514833272 @default.
- W101092216 cites W1515846068 @default.
- W101092216 cites W1528898535 @default.
- W101092216 cites W1541255368 @default.
- W101092216 cites W1569863959 @default.
- W101092216 cites W1580589705 @default.
- W101092216 cites W1605024297 @default.
- W101092216 cites W1675863551 @default.
- W101092216 cites W1841404836 @default.
- W101092216 cites W1893528652 @default.
- W101092216 cites W1899256833 @default.
- W101092216 cites W1905013483 @default.
- W101092216 cites W193927762 @default.
- W101092216 cites W1939799969 @default.
- W101092216 cites W1987665931 @default.
- W101092216 cites W1995339897 @default.
- W101092216 cites W2017297884 @default.
- W101092216 cites W2056336171 @default.
- W101092216 cites W2060507826 @default.
- W101092216 cites W2063703111 @default.
- W101092216 cites W2069421750 @default.
- W101092216 cites W2072725227 @default.
- W101092216 cites W2078347909 @default.
- W101092216 cites W2131233813 @default.
- W101092216 cites W2134674910 @default.
- W101092216 cites W2141211551 @default.
- W101092216 cites W2166376385 @default.
- W101092216 cites W2233541602 @default.
- W101092216 cites W2238035323 @default.
- W101092216 cites W2265586320 @default.
- W101092216 cites W2277351313 @default.
- W101092216 cites W2407557624 @default.
- W101092216 cites W2414360134 @default.
- W101092216 cites W2443699907 @default.
- W101092216 cites W2467737362 @default.
- W101092216 cites W2615721862 @default.
- W101092216 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1916326" @default.
- W101092216 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6859232" @default.
- W101092216 hasPublicationYear "1983" @default.
- W101092216 type Work @default.
- W101092216 sameAs 101092216 @default.
- W101092216 citedByCount "24" @default.
- W101092216 crossrefType "journal-article" @default.
- W101092216 hasAuthorship W101092216A5030934019 @default.
- W101092216 hasAuthorship W101092216A5041139639 @default.
- W101092216 hasAuthorship W101092216A5045100634 @default.
- W101092216 hasAuthorship W101092216A5049145562 @default.
- W101092216 hasAuthorship W101092216A5063812862 @default.
- W101092216 hasAuthorship W101092216A5066207319 @default.
- W101092216 hasAuthorship W101092216A5071304634 @default.
- W101092216 hasConcept C121332964 @default.
- W101092216 hasConcept C126322002 @default.
- W101092216 hasConcept C142724271 @default.
- W101092216 hasConcept C153400128 @default.
- W101092216 hasConcept C185592680 @default.
- W101092216 hasConcept C203014093 @default.
- W101092216 hasConcept C2776833585 @default.
- W101092216 hasConcept C2776914184 @default.
- W101092216 hasConcept C2777714996 @default.
- W101092216 hasConcept C2779020240 @default.
- W101092216 hasConcept C2780559512 @default.
- W101092216 hasConcept C2909420118 @default.
- W101092216 hasConcept C529295009 @default.
- W101092216 hasConcept C54173615 @default.
- W101092216 hasConcept C55493867 @default.
- W101092216 hasConcept C71924100 @default.
- W101092216 hasConcept C89560881 @default.
- W101092216 hasConcept C97355855 @default.
- W101092216 hasConceptScore W101092216C121332964 @default.
- W101092216 hasConceptScore W101092216C126322002 @default.
- W101092216 hasConceptScore W101092216C142724271 @default.
- W101092216 hasConceptScore W101092216C153400128 @default.
- W101092216 hasConceptScore W101092216C185592680 @default.
- W101092216 hasConceptScore W101092216C203014093 @default.
- W101092216 hasConceptScore W101092216C2776833585 @default.
- W101092216 hasConceptScore W101092216C2776914184 @default.
- W101092216 hasConceptScore W101092216C2777714996 @default.
- W101092216 hasConceptScore W101092216C2779020240 @default.
- W101092216 hasConceptScore W101092216C2780559512 @default.
- W101092216 hasConceptScore W101092216C2909420118 @default.
- W101092216 hasConceptScore W101092216C529295009 @default.
- W101092216 hasConceptScore W101092216C54173615 @default.
- W101092216 hasConceptScore W101092216C55493867 @default.
- W101092216 hasConceptScore W101092216C71924100 @default.
- W101092216 hasConceptScore W101092216C89560881 @default.
- W101092216 hasConceptScore W101092216C97355855 @default.