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• W1010978734 abstract "The gastrointestinal tract, affecting more than 90% of patients, is the internal organ most frequently involved in systemic sclerosis. Any part of the gastrointestinal tract can be affected, from the mouth to the anus. Patients often experience reduced quality of life and impaired social life. Although only 8% have severe gastrointestinal involvement, mortality is high in those patients. Recent studies on the pathophysiology of the disease highlight new mechanisms to explain gastrointestinal dysmotility, but treatment remains symptomatic. This article reviews the pathophysiology of the gastrointestinal tract and discusses the investigation and management of the disease." @default.
• W1010978734 created "2016-06-24" @default.
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• W1010978734 date "2015-08-01" @default.
• W1010978734 modified "2023-10-01" @default.
• W1010978734 title "Systemic Sclerosis" @default.
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• W1010978734 doi "https://doi.org/10.1016/j.rdc.2015.04.007" @default.
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