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- W1013027242 abstract "Under suitable conditions, it has been possible to subculture adult mammalian brain tissue, and from migration of the cells of the subcultured explant, to obtain more uniform subcultures consisting mainly of the migrated brain cells, which were originally present. Neurons retained their structural polarity, making it possible to identify perikarya, dendrites, axon hillock, axon, Nissl substance, neurofibrils, and acetylcholinesterase. Neurons formed associations among themselves with structures, which morphologically resembled very closely synapses observed in brain tissue, including synaptic knobs and rings, and specialized postsynaptic areas in the cell. Such synapses may be axodendritic or axe-somatic. Giant astrocytes are seen in cultures and subcultures of normal adult mammalian brain. These had morphological and staining properties, which made it possible to distinguish them from neurons. They did not show the polarity of neurons, and their giant processes could readily be distinguished from neuronal processes such as axons or dendrites. The free, unattached endings of astrocyte processes sometimes showed undulating membranes and pinocytosis." @default.
- W1013027242 created "2016-06-24" @default.
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- W1013027242 date "1963-01-01" @default.
- W1013027242 modified "2023-10-16" @default.
- W1013027242 title "The Behavior of Adult Mammalian Brain Cells in Culture" @default.
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- W1013027242 doi "https://doi.org/10.1016/s0074-7742(08)60593-0" @default.
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