FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1014994518> ?p ?o ?g. }

• W1014994518 endingPage "204" @default.
• W1014994518 startingPage "156" @default.
• W1014994518 abstract "This chapter discusses the modeling of side chains, loops, and insertions in proteins. It describes a hybrid approach to structural modeling that combines the detection, extension, and application of statistical trends in known protein structures with the identification of energetic fingerprints that characterize well-folded, globular proteins. All methods based on the application of statistical trends incur exceptions. However, the exceptions are also shown to follow readily identifiable statistical trends. To find and use the trends and fingerprints, side-chain and main-chain modeling can be considered to be loosely coupled problems that can be solved in an iterative fashion. The statistical trends show that relatively small databases comprised of well-determined, experimental structures are sufficient for many applications under two conditions. First, the databases must be representative of the modeling problems under consideration. Second, even high-resolution, well-refined structures are not of uniform quality. The chapter shows the way the statistical trends and energetic fingerprints can be combined to create main-chain and side-chain modeling methodologies that are generally applicable; these methods require significantly less disk storage space than conformational search methods, are CPU efficient, and generate model structures that are fully reproducible. The energetic fingerprints can frequently distinguish “incorrect” from “correct” structures and are relatively insensitive to small parameterization inconsistencies, simplified force field formulations, and coordinate errors typical of most modeling applications." @default.
• W1014994518 created "2016-06-24" @default.
• W1014994518 creator A5076499540 @default.
• W1014994518 creator A5081923767 @default.
• W1014994518 date "1991-01-01" @default.
• W1014994518 modified "2023-09-23" @default.
• W1014994518 title "[9] Modeling of side chains, loops, and insertions in proteins" @default.
• W1014994518 cites W1491345809 @default.
• W1014994518 cites W1496368635 @default.
• W1014994518 cites W1508885706 @default.
• W1014994518 cites W1516916562 @default.
• W1014994518 cites W1521782084 @default.
• W1014994518 cites W1535631466 @default.
• W1014994518 cites W1541008516 @default.
• W1014994518 cites W1565826566 @default.
• W1014994518 cites W1574312817 @default.
• W1014994518 cites W1598148918 @default.
• W1014994518 cites W1605897306 @default.
• W1014994518 cites W1606011614 @default.
• W1014994518 cites W1915528038 @default.
• W1014994518 cites W1963982969 @default.
• W1014994518 cites W1966679395 @default.
• W1014994518 cites W1966721068 @default.
• W1014994518 cites W1970180726 @default.
• W1014994518 cites W1970995363 @default.
• W1014994518 cites W1971251199 @default.
• W1014994518 cites W1971853518 @default.
• W1014994518 cites W1975832522 @default.
• W1014994518 cites W1976504548 @default.
• W1014994518 cites W1982679430 @default.
• W1014994518 cites W1984640820 @default.
• W1014994518 cites W1991261921 @default.
• W1014994518 cites W1992323841 @default.
• W1014994518 cites W2003331005 @default.
• W1014994518 cites W2008681847 @default.
• W1014994518 cites W2010458285 @default.
• W1014994518 cites W2017709960 @default.
• W1014994518 cites W2019076206 @default.
• W1014994518 cites W2019651515 @default.
• W1014994518 cites W2026185422 @default.
• W1014994518 cites W2030938300 @default.
• W1014994518 cites W2033227089 @default.
• W1014994518 cites W2033755909 @default.
• W1014994518 cites W2034038760 @default.
• W1014994518 cites W2036324972 @default.
• W1014994518 cites W2037231760 @default.
• W1014994518 cites W2038936167 @default.
• W1014994518 cites W2039388179 @default.
• W1014994518 cites W2040103443 @default.
• W1014994518 cites W2043885312 @default.
• W1014994518 cites W2045259048 @default.
• W1014994518 cites W2048961007 @default.
• W1014994518 cites W2051210276 @default.
• W1014994518 cites W2051920745 @default.
• W1014994518 cites W2052142083 @default.
• W1014994518 cites W2061881449 @default.
• W1014994518 cites W2061940650 @default.
• W1014994518 cites W2063971970 @default.
• W1014994518 cites W2066340206 @default.
• W1014994518 cites W2069843813 @default.
• W1014994518 cites W2074278124 @default.
• W1014994518 cites W2077235131 @default.
• W1014994518 cites W2081516433 @default.
• W1014994518 cites W2102376488 @default.
• W1014994518 cites W2106562139 @default.
• W1014994518 cites W2125793518 @default.
• W1014994518 cites W2149134776 @default.
• W1014994518 cites W2162166182 @default.
• W1014994518 cites W2179033920 @default.
• W1014994518 cites W2019130672 @default.
• W1014994518 doi "https://doi.org/10.1016/0076-6879(91)02011-w" @default.
• W1014994518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1784173" @default.
• W1014994518 hasPublicationYear "1991" @default.
• W1014994518 type Work @default.
• W1014994518 sameAs 1014994518 @default.
• W1014994518 citedByCount "17" @default.
• W1014994518 crossrefType "book-chapter" @default.
• W1014994518 hasAuthorship W1014994518A5076499540 @default.
• W1014994518 hasAuthorship W1014994518A5081923767 @default.
• W1014994518 hasConcept C11413529 @default.
• W1014994518 hasConcept C114289077 @default.
• W1014994518 hasConcept C116834253 @default.
• W1014994518 hasConcept C124101348 @default.
• W1014994518 hasConcept C154945302 @default.
• W1014994518 hasConcept C202444582 @default.
• W1014994518 hasConcept C33923547 @default.
• W1014994518 hasConcept C41008148 @default.
• W1014994518 hasConcept C59822182 @default.
• W1014994518 hasConcept C86803240 @default.
• W1014994518 hasConcept C9652623 @default.
• W1014994518 hasConceptScore W1014994518C11413529 @default.
• W1014994518 hasConceptScore W1014994518C114289077 @default.
• W1014994518 hasConceptScore W1014994518C116834253 @default.
• W1014994518 hasConceptScore W1014994518C124101348 @default.
• W1014994518 hasConceptScore W1014994518C154945302 @default.
• W1014994518 hasConceptScore W1014994518C202444582 @default.
• W1014994518 hasConceptScore W1014994518C33923547 @default.
• W1014994518 hasConceptScore W1014994518C41008148 @default.

• next