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- W1016973971 abstract "Publisher Summary The way the brain is built can be determined by following embryonic cells within the neural primordium while the complexity arises—that is, from the early stages of the neural plate up to the completion of neurogenesis. This involves the construction of fate maps and the tracing of neuroepithelial cells along their developmental history. This chapter presents a study in which movements and fate of the neuroepithelial territories were followed in the embryo (in ovo) during the entire period of development using the quail-chick chimera system. By using this system, the respective contributions of the alar and basal plates of the mes- and rhombencephalon to structures such as the cerebellum and various brain stem nuclei are determined. On the basis of the fate mapping results at the mid- and hindbrain levels and the combinations of the quail–chick chimerism with anti-bursal epithelium and neuron (BEN) immunoreactivity, it can be shown that the establishment of connections between the inferior olivary nucleus and Purkinje cells of the cerebellar cortex involves an immunoglobulin-like (Ig-like) cell-surface glycoprotein called BEN expression for the period of time corresponding to the growth of the climbing fibers and the onset of synaptogenesis. The developmental significance of these results is discussed in the chapter." @default.
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- W1016973971 title "Chapter 1 Cell migrations and establishment of neuronal connections in the developing brain: a study using the quail-chick chimera system" @default.
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- W1016973971 doi "https://doi.org/10.1016/s0079-6123(08)60762-1" @default.
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