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• W1020321814 abstract "Abstract BACKGROUND Researches on diabetic nervous system lesion are mainly focus on peripheral nerve and vegetative nerve, so there are few investigations on diabetic pseudotabes. OBJECTIVE To investigate the electrophysiological examinations on the diagnosis of diabetic pseudotabes. DESIGN Case study. SETTING Department of Electrophysiology and Department of Neurology, Zhongshan Hospital Affiliated to Xiamen University. PARTICIPANTS A total of 4 patients with type 2 diabetes mellitus, including 3 males and 1 female aged from 50 to 72 years, were selected from Department of Neurology, Zhongshan Hospital Affiliated to Xiamen University from March 2002 to February 2005. All accepted subjects met the modified diagnostic criteria of diabetes mellitus, which was set by American Diabetes Mellitus Association (ADA) in 1997. Otherwise, the subjects had typical symptoms and physical signs of spinal posterior funiculus damage. However, patients with spinal cord lesion which was caused by other factors were excluded. All accepted subjects provided the confirmed consent. METHODS Nicolet NT electromyography (EMG)/evoked potential meter (made in the USA) was used to detect spinal cord conduction velocity (SCCV), somatosensory evoked potential (SEP) of lower limbs, motor nerve conduction velocity (MNCV) and sensory nerve conduction velocity (SNCV) of extremities. Determining criteria: Measurements were performed based on the laboratory standards. SCCV, which was less than lower limit of normal value (T2–12: 40 – 55 m/s, T12 – L4: 20 – 41 m/s, T2 – L4: 36 – 45 m/s), was regarded as abnormal. SEP value of lower limbs: P40, P60 and PF, which were more than standard deviation of normal value (x+2.5), were regarded as the abnormality. Normal value of P40, P60 and PF latencies (x±s) in this study: P40, P60 and PF in males were (37.6±1.9) ms, (59.8±3.9) ms and (7.6±0.9) ms, respectively; meanwhile, those in females were (35.5±1.7) ms, (55.2±2.7) ms and (6.3±0.7) ms, respectively. MNCV and SNCV, which were less than 50 m/s in upper limbs and 40 m/s in lower limbs, were regarded as the abnormality. MAIN OUTCOME MEASURES Electrophysiological examinations. RESULTS All 4 patients with type 2 diabetes mellitus were involved in the final analysis. (1) SCCV: Among 4 patients, SCCV of three patients was decreased in T2 – 12, T12 – L4 and T2 – L4, and that of the other one was decreased in T2–12 and T2 – L4; however, SCCV in T12 – L4 was normal. There was significant difference as compared with normal value (P CONCLUSION Detections of SCCV, SEP of lower limbs, MNCV and SNCV of extremities are helpful to investigate whether peripheral nerve and deep sensory passage are damaged or not and determine whether deep sensory damage is caused by peripheral nerve and spinal posterior funiculus." @default.
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• W1020321814 date "2007-05-25" @default.
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• W1020321814 title "Electrophysiological evaluation in 4 patients with diabetic pseudotabes" @default.
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• W1020321814 doi "https://doi.org/10.1016/s1673-5374(20)30010-4" @default.
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