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- W1023538863 abstract "Prostacyclins are the first class of agents that showed efficacy in the treatment of pulmonary arterial hypertension (PAH) in a clinical trial and, for a long time, the only treatment specifically approved for this devastating disease. As new therapies have emerged for PAH in recent years, the class of prostacyclins has also evolved and several formulations of different prostacyclin analogs, using various routes of delivery, have been tested and shown to be efficacious in PAH. This chapter reviews the pharmacology of prostacyclins and the results of pivotal clinical trials testing various formulations. Lastly, it examines practical aspects of dosing, management of side effects, and expectations of treatment goals." @default.
- W1023538863 created "2016-06-24" @default.
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- W1023538863 date "2015-01-01" @default.
- W1023538863 modified "2023-09-24" @default.
- W1023538863 title "Prostacyclin Therapy for Pulmonary Arterial Hypertension" @default.
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- W1023538863 doi "https://doi.org/10.1007/978-1-4939-2636-7_13" @default.
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