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- W1023621276 endingPage "87" @default.
- W1023621276 startingPage "71" @default.
- W1023621276 abstract "Autism Spectrum Disorders are a heterogeneous group of neurodevelopmental disorders, with rising incidence but little effective therapeutic intervention available. Currently two main clinical features are described to diagnose ASDs: impaired social interaction and communication, and repetitive behaviors. Much work has focused on understanding underlying causes of ASD by generating animal models of the disease, in the hope of discovering signaling pathways and cellular targets for drug intervention. Here we review how ASD behavioral phenotypes can be modeled in the mouse, the most common animal model currently in use in this field, and discuss examples of genetic mouse models of ASD with behavioral features that recapitulate various symptoms of ASD." @default.
- W1023621276 created "2016-06-24" @default.
- W1023621276 creator A5038835317 @default.
- W1023621276 creator A5042710643 @default.
- W1023621276 creator A5046177527 @default.
- W1023621276 creator A5050192902 @default.
- W1023621276 creator A5069885337 @default.
- W1023621276 creator A5071939338 @default.
- W1023621276 creator A5073045452 @default.
- W1023621276 creator A5086204590 @default.
- W1023621276 date "2015-10-01" @default.
- W1023621276 modified "2023-10-06" @default.
- W1023621276 title "Autism Spectrum Disorders: Translating human deficits into mouse behavior" @default.
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