FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1024187829> ?p ?o ?g. }

• W1024187829 endingPage "224" @default.
• W1024187829 startingPage "217" @default.
• W1024187829 abstract "Photodynamic therapy, that is, excitation of a photosensitizer with light to generate reactive oxygen species such as singlet oxygen, has emerged as a noninvasive technique for cancer theranostics. However, the clinical use of many photosensitizers is impeded by their hydrophobicity, the nonspecific damage they cause to normal tissues, and their susceptibility to environmental degradation. In this study, we developed a simple electrostatic adsorption strategy to fabricate aptamer-silica nanocomposites by sequentially functionalizing nanocomposites with the cell surface-associated mucin 1 aptamer for tumor targeting and a hydrophilic photosensitizer, methylene blue, for photodynamic therapy applications. We investigated the relationship between the biophysical properties and cellular uptake of such nanocomposites to improve their formulation. Effective generation of singlet oxygen was achieved with a low photosensitizer dosage (0.5 μM) and a short, low-power irradiation (1 min, 10 mW/cm(2)). With the current strategy, the efficiency of photodynamic therapy was determined by the cellular uptake of nanocomposites and the targeting molecules used." @default.
• W1024187829 created "2016-06-24" @default.
• W1024187829 creator A5023028712 @default.
• W1024187829 creator A5048393431 @default.
• W1024187829 creator A5061561427 @default.
• W1024187829 creator A5065171021 @default.
• W1024187829 date "2015-11-01" @default.
• W1024187829 modified "2023-09-27" @default.
• W1024187829 title "In vitro investigation of methylene blue-bearing, electrostatically assembled aptamer–silica nanocomposites as potential photodynamic therapeutics" @default.
• W1024187829 cites W1916661321 @default.
• W1024187829 cites W1968277012 @default.
• W1024187829 cites W1971292240 @default.
• W1024187829 cites W1971533110 @default.
• W1024187829 cites W1971752921 @default.
• W1024187829 cites W1972077559 @default.
• W1024187829 cites W1988272953 @default.
• W1024187829 cites W1988497535 @default.
• W1024187829 cites W1999248402 @default.
• W1024187829 cites W2000201702 @default.
• W1024187829 cites W2001854786 @default.
• W1024187829 cites W2011300465 @default.
• W1024187829 cites W2015118757 @default.
• W1024187829 cites W2017296058 @default.
• W1024187829 cites W2020533972 @default.
• W1024187829 cites W2038974631 @default.
• W1024187829 cites W2046159336 @default.
• W1024187829 cites W2054496327 @default.
• W1024187829 cites W2059994307 @default.
• W1024187829 cites W2063819456 @default.
• W1024187829 cites W2068336234 @default.
• W1024187829 cites W2068695041 @default.
• W1024187829 cites W2070730931 @default.
• W1024187829 cites W2072181836 @default.
• W1024187829 cites W2073932571 @default.
• W1024187829 cites W2075556265 @default.
• W1024187829 cites W2083424582 @default.
• W1024187829 cites W2094811347 @default.
• W1024187829 cites W2097096352 @default.
• W1024187829 cites W2103311193 @default.
• W1024187829 cites W2126500509 @default.
• W1024187829 cites W2129360146 @default.
• W1024187829 cites W2133873308 @default.
• W1024187829 cites W2322266794 @default.
• W1024187829 cites W2330677824 @default.
• W1024187829 cites W2331494093 @default.
• W1024187829 cites W2332883373 @default.
• W1024187829 cites W4211024586 @default.
• W1024187829 cites W4237246631 @default.
• W1024187829 doi "https://doi.org/10.1016/j.colsurfb.2015.07.064" @default.
• W1024187829 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26255165" @default.
• W1024187829 hasPublicationYear "2015" @default.
• W1024187829 type Work @default.
• W1024187829 sameAs 1024187829 @default.
• W1024187829 citedByCount "13" @default.
• W1024187829 countsByYear W10241878292016 @default.
• W1024187829 countsByYear W10241878292017 @default.
• W1024187829 countsByYear W10241878292018 @default.
• W1024187829 countsByYear W10241878292019 @default.
• W1024187829 countsByYear W10241878292021 @default.
• W1024187829 countsByYear W10241878292022 @default.
• W1024187829 crossrefType "journal-article" @default.
• W1024187829 hasAuthorship W1024187829A5023028712 @default.
• W1024187829 hasAuthorship W1024187829A5048393431 @default.
• W1024187829 hasAuthorship W1024187829A5061561427 @default.
• W1024187829 hasAuthorship W1024187829A5065171021 @default.
• W1024187829 hasConcept C12554922 @default.
• W1024187829 hasConcept C128972844 @default.
• W1024187829 hasConcept C161790260 @default.
• W1024187829 hasConcept C171250308 @default.
• W1024187829 hasConcept C178790620 @default.
• W1024187829 hasConcept C185592680 @default.
• W1024187829 hasConcept C192562407 @default.
• W1024187829 hasConcept C2777516457 @default.
• W1024187829 hasConcept C2779191827 @default.
• W1024187829 hasConcept C2781323092 @default.
• W1024187829 hasConcept C2781469039 @default.
• W1024187829 hasConcept C540031477 @default.
• W1024187829 hasConcept C54355233 @default.
• W1024187829 hasConcept C65165184 @default.
• W1024187829 hasConcept C75473681 @default.
• W1024187829 hasConcept C86803240 @default.
• W1024187829 hasConcept C92880739 @default.
• W1024187829 hasConceptScore W1024187829C12554922 @default.
• W1024187829 hasConceptScore W1024187829C128972844 @default.
• W1024187829 hasConceptScore W1024187829C161790260 @default.
• W1024187829 hasConceptScore W1024187829C171250308 @default.
• W1024187829 hasConceptScore W1024187829C178790620 @default.
• W1024187829 hasConceptScore W1024187829C185592680 @default.
• W1024187829 hasConceptScore W1024187829C192562407 @default.
• W1024187829 hasConceptScore W1024187829C2777516457 @default.
• W1024187829 hasConceptScore W1024187829C2779191827 @default.
• W1024187829 hasConceptScore W1024187829C2781323092 @default.
• W1024187829 hasConceptScore W1024187829C2781469039 @default.
• W1024187829 hasConceptScore W1024187829C540031477 @default.
• W1024187829 hasConceptScore W1024187829C54355233 @default.
• W1024187829 hasConceptScore W1024187829C65165184 @default.
• W1024187829 hasConceptScore W1024187829C75473681 @default.
• W1024187829 hasConceptScore W1024187829C86803240 @default.

• next