Matches in SemOpenAlex for { <https://semopenalex.org/work/W1025492490> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W1025492490 endingPage "214" @default.
- W1025492490 startingPage "207" @default.
- W1025492490 abstract "Tissue samples from 166 primary and 136 metastatic breast cancers were analysed for the presence of estrogen receptors. It was found by measuring the affinity of the cytoplasmic fraction of these samples for 3H estradiol 17β that receptors were present in 72% and 54% of primary and metastatic cancers respectively. Receptor concentration varied among sample in an apparently continuous distribution from zero to 2,080 femtomoles per mg tissue protein. This suggests that mammary tumors are different from one another more in a quantitative than in a qualitative way. Detectable amounts of receptors were found in samples from mammary dysplasia, fibroadenomas as well as from one papilloma; none was detected in samples from non tumorous mammary glands, nipple, areola or skin. At mastectomy, no correlation was found between the presence or absence of receptors in the primary tumors, and presence or absence of metastatic axillary nodes. On the other hand both the primary and its axillary metastases almost always displayed the same characteristic as far as presence or absence of receptors was concerned. Analysis of clinical studies reported seems to indicate that women with advanced breast cancer respond in a fair proportion of cases to various endocrine treatments when tumor tissue biopsies contain estrogen receptors whereas the probability of a response is very low in their absence." @default.
- W1025492490 created "2016-06-24" @default.
- W1025492490 creator A5018313966 @default.
- W1025492490 creator A5057070339 @default.
- W1025492490 creator A5057856105 @default.
- W1025492490 creator A5082934839 @default.
- W1025492490 date "1975-01-01" @default.
- W1025492490 modified "2023-09-26" @default.
- W1025492490 title "LES RECEPTEURS HORMONAUX DES TUMEURS MALIGNES DU SEIN" @default.
- W1025492490 hasPublicationYear "1975" @default.
- W1025492490 type Work @default.
- W1025492490 sameAs 1025492490 @default.
- W1025492490 citedByCount "0" @default.
- W1025492490 crossrefType "journal-article" @default.
- W1025492490 hasAuthorship W1025492490A5018313966 @default.
- W1025492490 hasAuthorship W1025492490A5057070339 @default.
- W1025492490 hasAuthorship W1025492490A5057856105 @default.
- W1025492490 hasAuthorship W1025492490A5082934839 @default.
- W1025492490 hasConcept C121608353 @default.
- W1025492490 hasConcept C126322002 @default.
- W1025492490 hasConcept C134018914 @default.
- W1025492490 hasConcept C142724271 @default.
- W1025492490 hasConcept C170493617 @default.
- W1025492490 hasConcept C2775930923 @default.
- W1025492490 hasConcept C2777164284 @default.
- W1025492490 hasConcept C2778001805 @default.
- W1025492490 hasConcept C46699223 @default.
- W1025492490 hasConcept C530470458 @default.
- W1025492490 hasConcept C71315377 @default.
- W1025492490 hasConcept C71924100 @default.
- W1025492490 hasConcept C84606932 @default.
- W1025492490 hasConcept C86803240 @default.
- W1025492490 hasConceptScore W1025492490C121608353 @default.
- W1025492490 hasConceptScore W1025492490C126322002 @default.
- W1025492490 hasConceptScore W1025492490C134018914 @default.
- W1025492490 hasConceptScore W1025492490C142724271 @default.
- W1025492490 hasConceptScore W1025492490C170493617 @default.
- W1025492490 hasConceptScore W1025492490C2775930923 @default.
- W1025492490 hasConceptScore W1025492490C2777164284 @default.
- W1025492490 hasConceptScore W1025492490C2778001805 @default.
- W1025492490 hasConceptScore W1025492490C46699223 @default.
- W1025492490 hasConceptScore W1025492490C530470458 @default.
- W1025492490 hasConceptScore W1025492490C71315377 @default.
- W1025492490 hasConceptScore W1025492490C71924100 @default.
- W1025492490 hasConceptScore W1025492490C84606932 @default.
- W1025492490 hasConceptScore W1025492490C86803240 @default.
- W1025492490 hasLocation W10254924901 @default.
- W1025492490 hasOpenAccess W1025492490 @default.
- W1025492490 hasPrimaryLocation W10254924901 @default.
- W1025492490 hasVolume "4" @default.
- W1025492490 isParatext "false" @default.
- W1025492490 isRetracted "false" @default.
- W1025492490 magId "1025492490" @default.
- W1025492490 workType "article" @default.