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- W1026864032 abstract "Malaria disease is endemic in developing countries like Indonesia. This disease is caused by protozoa of the genus Plasmodium infection that is easily recognizable from the symptoms of prolonged fever. Some of the methods taken to stop spread of this disease. Artemisinin is a sesquiterpene lactone found in the leaves and flowers of plants Artemisia annua L and have different chemical structures and higher efficacy than others. Artemisia annua L. is originated from subtropical and can be introduced into the tropics such as Indonesia. The content of artemisinin itself is very small at around 0.01 to 1.4% of dry weight of plants. The first step in this research is solvent extraction using methanol. Step followed by partition using hexane and column chromatographic separation process with ethyl acetate / hexane as eluent. Isolates were characterized using TLC, FTIR, UV spectrophotometer, and HNMR spectroscopy. Through the process is obtained S4 as a result of isolation hexane fraction which has a character similar to artemisinin with 2.0 mg (0.016% w / w)" @default.
- W1026864032 created "2016-06-24" @default.
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- W1026864032 date "2012-01-01" @default.
- W1026864032 modified "2023-09-26" @default.
- W1026864032 title "Isolation of Artemisinin as Antimalarial Drugs from Artemisia annua L. Cultivated in Indonesia" @default.
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