Matches in SemOpenAlex for { <https://semopenalex.org/work/W103292242> ?p ?o ?g. }
- W103292242 endingPage "74" @default.
- W103292242 startingPage "74" @default.
- W103292242 abstract "Central neural circuits orchestrate a homeostatic repertoire to maintain body temperature during environmental temperature challenges and to alter body temperature during the inflammatory response. This review summarizes the functional organization of the neural pathways through which cutaneous thermal receptors alter thermoregulatory effectors: the cutaneous circulation for heat loss, the brown adipose tissue, skeletal muscle and heart for thermogenesis and species-dependent mechanisms (sweating, panting and saliva spreading) for evaporative heat loss. These effectors are regulated by parallel but distinct, effector-specific neural pathways that share a common peripheral thermal sensory input. The thermal afferent circuits include cutaneous thermal receptors, spinal dorsal horn neurons and lateral parabrachial nucleus neurons projecting to the preoptic area to influence warm-sensitive, inhibitory output neurons which control thermogenesis-promoting neurons in the dorsomedial hypothalamus that project to premotor neurons in the rostral ventromedial medulla, including the raphe pallidus, that descend to provide the excitation necessary to drive thermogenic thermal effectors. A distinct population of warm-sensitive preoptic neurons controls heat loss through an inhibitory input to raphe pallidus neurons controlling cutaneous vasoconstriction." @default.
- W103292242 created "2016-06-24" @default.
- W103292242 creator A5050828704 @default.
- W103292242 date "2011-01-01" @default.
- W103292242 modified "2023-10-03" @default.
- W103292242 title "Central neural pathways for thermoregulation" @default.
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