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- W1033997957 abstract "This chapter presents a survey on the biochemical changes observed in signalling and responding cells and on the resulting changes of cell shape and behavior in Dictyostelium. Dictyostelium discoideum is a microorganism that releases cyclic AMP as a chemotactic agent and a transmitter of propagated stimuli during its development from a unicellular to a multicellular state. The transmitter is generated periodically by virtue of oscillatory regulation of the synthesizing enzyme, and its lifetime in the intercellular space is limited by a hydrolyzing enzyme, cyclic AMP-phosphodiesterase. Development of the signal system is enhanced by its function. Association of the cells into a tissue-like assembly is mediated by a duplicate cell adhesion system. One component is a specific cell membrane glycoprotein. Its control by pulses of cAMP links the full expression of the adhesion system to this transmitter and to its recognition by cell surface receptors." @default.
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- W1033997957 date "1979-01-01" @default.
- W1033997957 modified "2023-09-27" @default.
- W1033997957 title "Cell Communication and Specific Adhesion in the Microorganism Dictyostelium" @default.
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- W1033997957 doi "https://doi.org/10.1016/s0079-6123(08)61289-3" @default.
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