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• W1035486752 abstract "Angiostrongylus cantonensis was first discovered in 1934 by Professor Chen Xintao and has become an important emerging pathogen causing human angiostrongyliasis. Rats are permissive host, and mice and human are non-permissive host. The adult worms live in the right ventricle and pulmonary arteries of rats. However, worms can’t develop to adult worm and the IV and V stage worm live in brain of mice and human. Human infect this disease by eating raw or undercooked snails or slugs, paratenic host such as prawns or contaminated vegetables, and water that contain the infective larvae. A. cantonensis has spread from its traditional endemic regions of the Pacific islands and Southeast Asia to the American continent including the USA, Caribbean islands, and Brazil. During the past few years, major outbreaks of human angiostrongyliasis have been reported in mainland China, Taiwan, Thailand, Ecuadorian, French, Germany, India, and Jamaica. Additionally, sporadic cases in travelers who have returned from endemic areas have been reported. Thousands of cases of human angiostrongyliasis have been documented worldwide. The main clinical manifestations of human angiostrongyliasis are eosinophilic meningitis and ocular angiostrongyliasis. In adult patients, the common symptoms were headache, neck stiffness, paresthesia, vomiting, and nausea. The treatment of this disease includes supportive treatment, corticosteroid therapy, and combined therapy with corticosteroids and anthelminthics. However, it is pity that some patients have sequela after treated. Therefore, some new drugs like Chinese herbal medicine have been studied for therapy angiostrongyliasis. The basic research is very important for better solution of angiostrongyliasis, so more and more study are in process, which involve mechanism of brain inflammation, new drugs finding, protein and gene sequence and analysis, new diagnosis method exploring, etc. Whatever, persuading people not to eat raw or undercooked intermediate and paratenic hosts is the most effective method for prevention and control angiostrongyliasis." @default.
• W1035486752 created "2016-06-24" @default.
• W1035486752 creator A5013382299 @default.
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• W1035486752 date "2013-08-22" @default.
• W1035486752 modified "2023-09-25" @default.
• W1035486752 title "Angiostrongylus cantonensis in China" @default.
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• W1035486752 doi "https://doi.org/10.1007/978-3-642-39824-7_14" @default.
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