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- W103617042 abstract "Publisher Summary This chapter provides an overview of the direct identification and characterization of β-adrenergic receptors and functional relationship of adenylyl cyclase. Since the past several years, a variety of radioactive ligands have been employed to identify hormone receptors in a number of different tissues. Earlier attempts to study β-adrenergic interactions with labeled agonists met with methodologie problems, including lack of stereospecificity and poor correlation between the binding data and biological effects. However, recently the development of high-specific-activity radioactive β-adrenergic blockers has permitted the identification of β-receptors with the properties expected from the physiological studies, including saturability, strict stereospecificity, and parallelism between inhibition of tracer binding and activation or inhibition of adenylyl cyclase." @default.
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- W103617042 date "1978-01-01" @default.
- W103617042 modified "2023-09-27" @default.
- W103617042 title "Direct Identification and Characterization of β-Adrenergic Receptors and Functional Relationship of Adenylyl Cyclase" @default.
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- W103617042 doi "https://doi.org/10.1016/b978-0-12-526303-0.50010-2" @default.
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