Matches in SemOpenAlex for { <https://semopenalex.org/work/W103631269> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W103631269 abstract "THE EFFECT OF FOCUSED EXTRACORPOREAL SHOCK WAVE (ESW) ON CALVARIA BONE EX VIVO Syrah Quraishi, DDS Marquette University, 2013 Introduction: Extracorporeal shock wave (ESW) is low frequency high-pressure wave, regularly used to destroy calcifications e.g. kidney stone. Recent evidence shows that ESW produces micro-cracks in the bones of horse legs. As micro-cracks in bone can lead to an increased rate of bone turnover (remodeling), we hypothesize that proper application of ESW will increase bone turnover rate through generating micro-cracks in bone. Materials and Methods: To test our hypothesis, we used a mouse calvaria bone organ culture model and explored the effects of ESW on bone tissues ex vivo. The calvaria bone pieces were collected from 3 days old C57BL/6 neonatal mice and cultured in 10% FBS supplemented DMEM. After dissection, each quadrant (1/4) of calvaria was randomly assigned into one control and three experimental groups which were subjected to a single dose of 2000 shocks of 3 energy levels of ESW i.e. low (0.1mJ/mm2, 6 Hz), medium (0.25mJ/mm2, 4 Hz), and high (0.5mJ/mm2, 3 Hz,) doses, respectively. After ESW stimulation, the bone tissues were further cultured for 1 week and fixed in 10% formalin. The same experiment was repeated three times (n=3). The bone samples were (1) examined by using a customized radiographic analysis program to measure the bone microdensity, and (2) demineralized and processed to undergo H&E staining to observe the cellular changes histologically. Results: Radiographically the mid dose group exhibited a higher microdensity but not statistically significant (P > 0.05) compared to the other two ESW and the control groups. Histologically, some empty osteocytic lacunae exhibited in all the three dose ESW groups, with nearly all osteocytes disappeared in the high dose group. Hypertrophy of osteoblasts was mainly found in the low dose group. No microcracks were observed on all the H&E staining tissue slides. Histological differences cannot be calculated statistically mainly due to the high heterogeneity of the samples. Conclusion: Although not statistically significant, the mid dose ESW group seems to gain bone microdensity. Due to the lack of statistical differences, definite conclusions cannot be drawn, leaving further endeavors be put on this topic." @default.
- W103631269 created "2016-06-24" @default.
- W103631269 creator A5031998534 @default.
- W103631269 date "2013-01-01" @default.
- W103631269 modified "2023-09-27" @default.
- W103631269 title "The Effect Of Focused Extracorporeal Shock Wave (ESW) On Calvaria Bone Ex Vivo" @default.
- W103631269 cites W141560187 @default.
- W103631269 cites W181600556 @default.
- W103631269 cites W1900951750 @default.
- W103631269 cites W1968641756 @default.
- W103631269 cites W1968872980 @default.
- W103631269 cites W1976815400 @default.
- W103631269 cites W1978239393 @default.
- W103631269 cites W1978322517 @default.
- W103631269 cites W1992294851 @default.
- W103631269 cites W1993446831 @default.
- W103631269 cites W2007107308 @default.
- W103631269 cites W2019582558 @default.
- W103631269 cites W2022903951 @default.
- W103631269 cites W2026281468 @default.
- W103631269 cites W2033466425 @default.
- W103631269 cites W2053999728 @default.
- W103631269 cites W2054596963 @default.
- W103631269 cites W2054818494 @default.
- W103631269 cites W2055515562 @default.
- W103631269 cites W2061727589 @default.
- W103631269 cites W2074219804 @default.
- W103631269 cites W2075863706 @default.
- W103631269 cites W2076345112 @default.
- W103631269 cites W2079822989 @default.
- W103631269 cites W2080044233 @default.
- W103631269 cites W2084566277 @default.
- W103631269 cites W2085645187 @default.
- W103631269 cites W2099743160 @default.
- W103631269 cites W2102445353 @default.
- W103631269 cites W2108956625 @default.
- W103631269 cites W2111365448 @default.
- W103631269 cites W2114586992 @default.
- W103631269 cites W2123934184 @default.
- W103631269 cites W2139045027 @default.
- W103631269 cites W2140622752 @default.
- W103631269 cites W2147725955 @default.
- W103631269 cites W2148864630 @default.
- W103631269 cites W2161123679 @default.
- W103631269 cites W2168337577 @default.
- W103631269 cites W2295149035 @default.
- W103631269 cites W2311672730 @default.
- W103631269 cites W2416311396 @default.
- W103631269 cites W2429831521 @default.
- W103631269 cites W2443453695 @default.
- W103631269 cites W3025739795 @default.
- W103631269 cites W42425327 @default.
- W103631269 cites W438961016 @default.
- W103631269 hasPublicationYear "2013" @default.
- W103631269 type Work @default.
- W103631269 sameAs 103631269 @default.
- W103631269 citedByCount "0" @default.
- W103631269 crossrefType "journal-article" @default.
- W103631269 hasAuthorship W103631269A5031998534 @default.
- W103631269 hasConcept C105702510 @default.
- W103631269 hasConcept C126322002 @default.
- W103631269 hasConcept C141071460 @default.
- W103631269 hasConcept C150903083 @default.
- W103631269 hasConcept C170033053 @default.
- W103631269 hasConcept C185592680 @default.
- W103631269 hasConcept C202751555 @default.
- W103631269 hasConcept C207001950 @default.
- W103631269 hasConcept C26291073 @default.
- W103631269 hasConcept C2779915274 @default.
- W103631269 hasConcept C2779918246 @default.
- W103631269 hasConcept C55493867 @default.
- W103631269 hasConcept C71924100 @default.
- W103631269 hasConcept C8337478 @default.
- W103631269 hasConcept C86803240 @default.
- W103631269 hasConceptScore W103631269C105702510 @default.
- W103631269 hasConceptScore W103631269C126322002 @default.
- W103631269 hasConceptScore W103631269C141071460 @default.
- W103631269 hasConceptScore W103631269C150903083 @default.
- W103631269 hasConceptScore W103631269C170033053 @default.
- W103631269 hasConceptScore W103631269C185592680 @default.
- W103631269 hasConceptScore W103631269C202751555 @default.
- W103631269 hasConceptScore W103631269C207001950 @default.
- W103631269 hasConceptScore W103631269C26291073 @default.
- W103631269 hasConceptScore W103631269C2779915274 @default.
- W103631269 hasConceptScore W103631269C2779918246 @default.
- W103631269 hasConceptScore W103631269C55493867 @default.
- W103631269 hasConceptScore W103631269C71924100 @default.
- W103631269 hasConceptScore W103631269C8337478 @default.
- W103631269 hasConceptScore W103631269C86803240 @default.
- W103631269 hasLocation W1036312691 @default.
- W103631269 hasOpenAccess W103631269 @default.
- W103631269 hasPrimaryLocation W1036312691 @default.
- W103631269 hasRelatedWork W1990043511 @default.
- W103631269 hasRelatedWork W2001650559 @default.
- W103631269 hasRelatedWork W2066091095 @default.
- W103631269 hasRelatedWork W2464621326 @default.
- W103631269 isParatext "false" @default.
- W103631269 isRetracted "false" @default.
- W103631269 magId "103631269" @default.
- W103631269 workType "article" @default.