Matches in SemOpenAlex for { <https://semopenalex.org/work/W1038231257> ?p ?o ?g. }
- W1038231257 endingPage "235" @default.
- W1038231257 startingPage "201" @default.
- W1038231257 abstract "Publisher Summary This chapter summarizes the results of attempts to identify and isolate tumor antigens. The study of tumor-associated antigens presents two major problems for a tumor biologist. The first concerns their chemical structure and the second concerns the basis for their unusual interaction with the immune system. Tumor specific antigens— tumor associated transplantation antigens (TATA) or tumor-specific surface antigens (TSSA)—from several types of neoplasms of the mouse (those induced by chemical carcinogens and those induced by the DNA-containing and RNA-containing oncogenic viruses) can be obtained in soluble form and maintain the specific immunogenic activity of the intact cell. Chromatographic fractionation of the solubilized material allows for the separation of TATA or membrane-associated TSSA from other antigens, for example, from H-2 and from the murine leukemia virus (MuLV)-related antigens. A remarkable feature of TATAs of chemically induced tumors is their polymorphism. The genetic origin of these antigens has been amply discussed, and a commonly held view is that they represent products of derepressed or mutated genes. An analysis of the nature of the immune response to tumor antigens, with emphasis on their molecular structure, provides new methods for an immunological approach to the understanding and control of human cancer." @default.
- W1038231257 created "2016-06-24" @default.
- W1038231257 creator A5034888318 @default.
- W1038231257 creator A5036354240 @default.
- W1038231257 creator A5081312172 @default.
- W1038231257 date "1980-01-01" @default.
- W1038231257 modified "2023-09-23" @default.
- W1038231257 title "Tumor Antigens on Neoplasms Induced by Chemical Carcinogens and by DNA- and RNA-Containing Viruses: Properties of the Solubilized Antigens" @default.
- W1038231257 cites W1485785639 @default.
- W1038231257 cites W1489835538 @default.
- W1038231257 cites W1490578488 @default.
- W1038231257 cites W1496475839 @default.
- W1038231257 cites W1501109697 @default.
- W1038231257 cites W1521327829 @default.
- W1038231257 cites W1541280749 @default.
- W1038231257 cites W1559919151 @default.
- W1038231257 cites W1583045824 @default.
- W1038231257 cites W1583381699 @default.
- W1038231257 cites W1760544988 @default.
- W1038231257 cites W1810409544 @default.
- W1038231257 cites W1837934492 @default.
- W1038231257 cites W1919769015 @default.
- W1038231257 cites W1921046715 @default.
- W1038231257 cites W1959974800 @default.
- W1038231257 cites W1964133052 @default.
- W1038231257 cites W1965768817 @default.
- W1038231257 cites W1966880010 @default.
- W1038231257 cites W1969267791 @default.
- W1038231257 cites W1970330977 @default.
- W1038231257 cites W1971573851 @default.
- W1038231257 cites W1973224141 @default.
- W1038231257 cites W1978903078 @default.
- W1038231257 cites W1981777490 @default.
- W1038231257 cites W1982347860 @default.
- W1038231257 cites W1987526354 @default.
- W1038231257 cites W1988297269 @default.
- W1038231257 cites W1989430570 @default.
- W1038231257 cites W1990189083 @default.
- W1038231257 cites W1990394302 @default.
- W1038231257 cites W1990943787 @default.
- W1038231257 cites W1994112021 @default.
- W1038231257 cites W1994419334 @default.
- W1038231257 cites W1994931662 @default.
- W1038231257 cites W2000641451 @default.
- W1038231257 cites W2001154313 @default.
- W1038231257 cites W2001285899 @default.
- W1038231257 cites W2001336440 @default.
- W1038231257 cites W2001727345 @default.
- W1038231257 cites W2004605747 @default.
- W1038231257 cites W2005358206 @default.
- W1038231257 cites W2007976169 @default.
- W1038231257 cites W2009041428 @default.
- W1038231257 cites W2010476811 @default.
- W1038231257 cites W2015798972 @default.
- W1038231257 cites W2018958019 @default.
- W1038231257 cites W2022574145 @default.
- W1038231257 cites W2023088246 @default.
- W1038231257 cites W2024344753 @default.
- W1038231257 cites W2025275711 @default.
- W1038231257 cites W2029693024 @default.
- W1038231257 cites W2032679084 @default.
- W1038231257 cites W2032849134 @default.
- W1038231257 cites W2033983118 @default.
- W1038231257 cites W2033996791 @default.
- W1038231257 cites W2034050798 @default.
- W1038231257 cites W2035111364 @default.
- W1038231257 cites W2035168457 @default.
- W1038231257 cites W2041007322 @default.
- W1038231257 cites W2043909612 @default.
- W1038231257 cites W2048180995 @default.
- W1038231257 cites W2049046208 @default.
- W1038231257 cites W2049527615 @default.
- W1038231257 cites W2049866812 @default.
- W1038231257 cites W2050646004 @default.
- W1038231257 cites W2059119475 @default.
- W1038231257 cites W2059638094 @default.
- W1038231257 cites W2063084750 @default.
- W1038231257 cites W2063437562 @default.
- W1038231257 cites W2063719622 @default.
- W1038231257 cites W2064671301 @default.
- W1038231257 cites W2066459417 @default.
- W1038231257 cites W2066899488 @default.
- W1038231257 cites W2068708207 @default.
- W1038231257 cites W2073012116 @default.
- W1038231257 cites W2073139538 @default.
- W1038231257 cites W2075138594 @default.
- W1038231257 cites W2077899923 @default.
- W1038231257 cites W2078572835 @default.
- W1038231257 cites W2078583026 @default.
- W1038231257 cites W2081541692 @default.
- W1038231257 cites W2083942843 @default.
- W1038231257 cites W2088764537 @default.
- W1038231257 cites W2089008744 @default.
- W1038231257 cites W2100445430 @default.
- W1038231257 cites W2101666327 @default.
- W1038231257 cites W2107333092 @default.
- W1038231257 cites W2107403957 @default.
- W1038231257 cites W2123291376 @default.