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- W1038585844 abstract "The role of angiogenesis in tumor growth has been studied continuously for over 45 years. It is now appreciated that angiogenesis is also essential for the dissemination and establishment of tumor metastases. In this review, we focus on the role of angiogenesis as a necessity for the escape of tumor cells into the bloodstream and for the establishment of metastatic colonies in secondary sites. We also discuss the role of tumor lymphangiogenesis as a means of dissemination of lymphatic metastases. Appropriate combination therapies may be used in the future to both prevent and treat metastatic disease through the rational use of antiangiogenic and antilymphangiogenic therapies in ways that are informed by the current and future work in the field." @default.
- W1038585844 created "2016-06-24" @default.
- W1038585844 creator A5032324140 @default.
- W1038585844 creator A5059413396 @default.
- W1038585844 date "2015-07-01" @default.
- W1038585844 modified "2023-10-14" @default.
- W1038585844 title "The Contribution of Angiogenesis to the Process of Metastasis" @default.
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- W1038585844 doi "https://doi.org/10.1097/ppo.0000000000000138" @default.
- W1038585844 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4670555" @default.
- W1038585844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26222078" @default.
- W1038585844 hasPublicationYear "2015" @default.
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