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- W1039935711 abstract "Publisher Summary This chapter discusses the findings obtained from studies conducted on a number of inflammatory diseases using the immunoperoxidase technique to detect immunoglobulin-containing (Ig) cells, and in some cases, viral antigens within central nervous system (CNS) material. The material examined consisted almost entirely of sections of brains and spinal cords obtained at autopsy, fixed in 10% neutral formalin, and embedded in paraffin wax. In some cases, the material was used after many years of storage either in formalin or in paraffin wax. In the case of herpes, simplex encephalitis (HSE) and subacute sclerosing panencephalitis (SSPE) additional sections were stained with a rabbit antiserum to herpes simplex virus (type l), and measles virus respectively. Control sections were treated with either normal rabbit serum, antilysozyme antibody, or with the above antisera preabsorbed with the appropriate antigen. With cases of SSPE, poliomyelitis and multiple sclerosis (MS) quantification of the numbers of nucleated cells with a rounded cytoplasmic outline staining strongly for each of the immunoglobulin determinants was carried out by systematically scanning equivalent areas and counting the stained cells in each of the serial sections. This was done in pathologically damaged and undamaged areas in multiple sclerosis and poliomyelitis. Results were compared by a nonparametric statistical test." @default.
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- W1039935711 date "1983-01-01" @default.
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- W1039935711 title "Immunohistological studies of immunoglobulin-containing cells and viral antigens in some inflammatory diseases of the nervous system." @default.
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