Matches in SemOpenAlex for { <https://semopenalex.org/work/W1040049628> ?p ?o ?g. }
- W1040049628 endingPage "577" @default.
- W1040049628 startingPage "577" @default.
- W1040049628 abstract "We have previously shown that acute traumatic brain injury (TBI) is accompanied by increased level of circulating bone marrow progenitors, and favorable outcome is associated with early mobilization of CD34+CD45+ hematopoietic progenitor cells (HP). The present study was aimed at investigating whether patients with early HP mobilization differed from those with mobilization failure by systemic inflammatory reaction and immune parameters. The TBI patients were characterized by increased levels of serum C-reactive protein (CRP), IL-1в, IL-6, IL-8, MCP-1, G-CSF and IL-1ra indicative for presence of systemic inflammatory response. Importantly, patients with lacking mobilization of early HPs were shown to have significantly higher serum levels of CRP, MCP-1, MIP-1в, and G-CSF and a lower level of VEGF. In addition, patients with lack of early HP mobilization differed by significantly lower absolute number of lymphocytes, CD3+ T cells, CD4+ T cells, CD16+ NK cells and proliferative response of mononuclear cells to stimulation with ConA as well as by 4-fold higher rate of infectious complications compared with the opposite group. These data suggest that correlation of early mobilization of CD34+CD45+ cells with a favorable outcome in TBI patients may be partially mediated by anti-inflammatory and immunomodulatory effects of circulating bone marrow progenitors." @default.
- W1040049628 created "2016-06-24" @default.
- W1040049628 creator A5010400979 @default.
- W1040049628 creator A5024053027 @default.
- W1040049628 creator A5029223758 @default.
- W1040049628 creator A5046096418 @default.
- W1040049628 creator A5052402609 @default.
- W1040049628 creator A5067050682 @default.
- W1040049628 creator A5088420494 @default.
- W1040049628 date "2015-01-27" @default.
- W1040049628 modified "2023-09-26" @default.
- W1040049628 title "IMMUNOMODULATORY EFFECT OF CIRCULATING BONE MARROW PROGENITORS AS A POSSIBLE MECHANISM OF NEUROPROTECTION IN TRAUMATIC BRAIN INJURY" @default.
- W1040049628 cites W1534479115 @default.
- W1040049628 cites W1981127449 @default.
- W1040049628 cites W1992537109 @default.
- W1040049628 cites W1995483670 @default.
- W1040049628 cites W2006204222 @default.
- W1040049628 cites W2009178440 @default.
- W1040049628 cites W2010915352 @default.
- W1040049628 cites W2011593242 @default.
- W1040049628 cites W2020001113 @default.
- W1040049628 cites W2029491035 @default.
- W1040049628 cites W2037418955 @default.
- W1040049628 cites W2041288820 @default.
- W1040049628 cites W2054382953 @default.
- W1040049628 cites W2056793603 @default.
- W1040049628 cites W2061731737 @default.
- W1040049628 cites W2068352803 @default.
- W1040049628 cites W2099078833 @default.
- W1040049628 cites W2102931926 @default.
- W1040049628 cites W2109157584 @default.
- W1040049628 cites W2116505148 @default.
- W1040049628 cites W2121567769 @default.
- W1040049628 cites W2135463621 @default.
- W1040049628 cites W2151032082 @default.
- W1040049628 cites W2152854915 @default.
- W1040049628 cites W2165695867 @default.
- W1040049628 cites W2265832683 @default.
- W1040049628 cites W1965637986 @default.
- W1040049628 doi "https://doi.org/10.15789/1563-0625-2014-6-577-586" @default.
- W1040049628 hasPublicationYear "2015" @default.
- W1040049628 type Work @default.
- W1040049628 sameAs 1040049628 @default.
- W1040049628 citedByCount "0" @default.
- W1040049628 crossrefType "journal-article" @default.
- W1040049628 hasAuthorship W1040049628A5010400979 @default.
- W1040049628 hasAuthorship W1040049628A5024053027 @default.
- W1040049628 hasAuthorship W1040049628A5029223758 @default.
- W1040049628 hasAuthorship W1040049628A5046096418 @default.
- W1040049628 hasAuthorship W1040049628A5052402609 @default.
- W1040049628 hasAuthorship W1040049628A5067050682 @default.
- W1040049628 hasAuthorship W1040049628A5088420494 @default.
- W1040049628 hasBestOaLocation W10400496281 @default.
- W1040049628 hasConcept C10205521 @default.
- W1040049628 hasConcept C109159458 @default.
- W1040049628 hasConcept C126322002 @default.
- W1040049628 hasConcept C137061746 @default.
- W1040049628 hasConcept C156708679 @default.
- W1040049628 hasConcept C166957645 @default.
- W1040049628 hasConcept C201750760 @default.
- W1040049628 hasConcept C202751555 @default.
- W1040049628 hasConcept C203014093 @default.
- W1040049628 hasConcept C25498285 @default.
- W1040049628 hasConcept C2776914184 @default.
- W1040049628 hasConcept C2780007613 @default.
- W1040049628 hasConcept C28328180 @default.
- W1040049628 hasConcept C54355233 @default.
- W1040049628 hasConcept C55493867 @default.
- W1040049628 hasConcept C71924100 @default.
- W1040049628 hasConcept C86803240 @default.
- W1040049628 hasConcept C8891405 @default.
- W1040049628 hasConcept C95457728 @default.
- W1040049628 hasConceptScore W1040049628C10205521 @default.
- W1040049628 hasConceptScore W1040049628C109159458 @default.
- W1040049628 hasConceptScore W1040049628C126322002 @default.
- W1040049628 hasConceptScore W1040049628C137061746 @default.
- W1040049628 hasConceptScore W1040049628C156708679 @default.
- W1040049628 hasConceptScore W1040049628C166957645 @default.
- W1040049628 hasConceptScore W1040049628C201750760 @default.
- W1040049628 hasConceptScore W1040049628C202751555 @default.
- W1040049628 hasConceptScore W1040049628C203014093 @default.
- W1040049628 hasConceptScore W1040049628C25498285 @default.
- W1040049628 hasConceptScore W1040049628C2776914184 @default.
- W1040049628 hasConceptScore W1040049628C2780007613 @default.
- W1040049628 hasConceptScore W1040049628C28328180 @default.
- W1040049628 hasConceptScore W1040049628C54355233 @default.
- W1040049628 hasConceptScore W1040049628C55493867 @default.
- W1040049628 hasConceptScore W1040049628C71924100 @default.
- W1040049628 hasConceptScore W1040049628C86803240 @default.
- W1040049628 hasConceptScore W1040049628C8891405 @default.
- W1040049628 hasConceptScore W1040049628C95457728 @default.
- W1040049628 hasIssue "6" @default.
- W1040049628 hasLocation W10400496281 @default.
- W1040049628 hasOpenAccess W1040049628 @default.
- W1040049628 hasPrimaryLocation W10400496281 @default.
- W1040049628 hasRelatedWork W2033570110 @default.
- W1040049628 hasRelatedWork W2063113696 @default.
- W1040049628 hasRelatedWork W2158356837 @default.