Matches in SemOpenAlex for { <https://semopenalex.org/work/W104173885> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W104173885 endingPage "5" @default.
- W104173885 startingPage "2241" @default.
- W104173885 abstract "The authors studied the hemodynamics of 5-FU hepatoarterial infusion in a colorectal cancer patient with multiple liver metastases, who had chronic renal failure maintained by hemodialysis. Under weekly high dose 5-FU hepatoarterial infusion (1,000 mg/m2, 5 hours), on a non-dialysis day, serum 5-FU concentration was 1,090 ng/ml just after the 5 h infusion, 391 ng/ml at 15 min, 217 ng/ml at 30 min, 47 ng/ml at 60 min, and < 4 ng/ml at 120 min after infusion. On a dialysis day it was 1,500 ng/ml just after infusion, 41 ng/ml at 15 min, 5 ng/ml at 30 min, and < 4 ng/ml at 60 and 120 min after infusion. A control group (n = 4), who had liver metastases from colorectal cancers and normal renal functions, showed 5-FU serum concentration of 987 +/- 384 ng/ml just after infusion, 226 +/- 117 ng/ml at 15 min, 18.5 +/- 5.8 ng/ml at 30 min, < 4 ng/ml at 60 and 120 min after infusion. The serum 5-FU concentration of the patient was maintained higher on non-dialysis days, while it decreased more rapidly on dialysis days than that of the control group. There were no clinical complications due to the weekly high dose 5-FU hepatoarterial infusion. Under the treatment of continuous 5-FU hepatoarterial infusion (500 mg/day), the serum 5-FU concentration of this patient was kept under 115 ng/ml. After hemodialysis, the concentration decreased. The serum 5-FU concentration of the control group (n = 4) was under 66 ng/ml. There were no side effects under the protocol of continuous 5-FU hepatoarterial infusion. 5-FU hepatoarterial infusion for liver metastasis was a safe treatment for a renal failure patient with hemodialysis." @default.
- W104173885 created "2016-06-24" @default.
- W104173885 creator A5004905771 @default.
- W104173885 creator A5021509112 @default.
- W104173885 creator A5027388901 @default.
- W104173885 creator A5037231958 @default.
- W104173885 creator A5072826605 @default.
- W104173885 creator A5086255411 @default.
- W104173885 date "1999-12-01" @default.
- W104173885 modified "2023-09-23" @default.
- W104173885 title "[Hemodynamics at hepatoarterial infusion of 5-FU in a chronic renal failure patient maintained by hemodialysis]." @default.
- W104173885 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10635312" @default.
- W104173885 hasPublicationYear "1999" @default.
- W104173885 type Work @default.
- W104173885 sameAs 104173885 @default.
- W104173885 citedByCount "1" @default.
- W104173885 countsByYear W1041738852015 @default.
- W104173885 crossrefType "journal-article" @default.
- W104173885 hasAuthorship W104173885A5004905771 @default.
- W104173885 hasAuthorship W104173885A5021509112 @default.
- W104173885 hasAuthorship W104173885A5027388901 @default.
- W104173885 hasAuthorship W104173885A5037231958 @default.
- W104173885 hasAuthorship W104173885A5072826605 @default.
- W104173885 hasAuthorship W104173885A5086255411 @default.
- W104173885 hasConcept C126894567 @default.
- W104173885 hasConcept C141071460 @default.
- W104173885 hasConcept C178853913 @default.
- W104173885 hasConcept C2778063415 @default.
- W104173885 hasConcept C2779978075 @default.
- W104173885 hasConcept C2993356106 @default.
- W104173885 hasConcept C3018112808 @default.
- W104173885 hasConcept C42219234 @default.
- W104173885 hasConcept C71924100 @default.
- W104173885 hasConceptScore W104173885C126894567 @default.
- W104173885 hasConceptScore W104173885C141071460 @default.
- W104173885 hasConceptScore W104173885C178853913 @default.
- W104173885 hasConceptScore W104173885C2778063415 @default.
- W104173885 hasConceptScore W104173885C2779978075 @default.
- W104173885 hasConceptScore W104173885C2993356106 @default.
- W104173885 hasConceptScore W104173885C3018112808 @default.
- W104173885 hasConceptScore W104173885C42219234 @default.
- W104173885 hasConceptScore W104173885C71924100 @default.
- W104173885 hasIssue "14" @default.
- W104173885 hasLocation W1041738851 @default.
- W104173885 hasOpenAccess W104173885 @default.
- W104173885 hasPrimaryLocation W1041738851 @default.
- W104173885 hasRelatedWork W104173885 @default.
- W104173885 hasRelatedWork W1991794087 @default.
- W104173885 hasRelatedWork W2008374734 @default.
- W104173885 hasRelatedWork W2077735452 @default.
- W104173885 hasRelatedWork W2235503669 @default.
- W104173885 hasRelatedWork W2363908136 @default.
- W104173885 hasRelatedWork W2589996481 @default.
- W104173885 hasRelatedWork W2948312773 @default.
- W104173885 hasRelatedWork W4247614487 @default.
- W104173885 hasRelatedWork W2304521611 @default.
- W104173885 hasVolume "26" @default.
- W104173885 isParatext "false" @default.
- W104173885 isRetracted "false" @default.
- W104173885 magId "104173885" @default.
- W104173885 workType "article" @default.