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- W1042196395 abstract "Beginning in the late 1950s into the 1970s the laboratories of El-wood Jensen and Jack Gorski proposed a model by which the inter-action of the receptor and 17s-estradiol (E2) are involved in transducing the cellular effects of this hormone (Jensen and DeSombre 1973; Toft and Gorski 1966). Their laboratories also performed the isolation and initial characterization of the estrogen receptor (ER; Jensen and DeSombre 1973; Toft and Gorski 1966). Since its initial discovery, significant progress has been made in understanding the mechanisms and manifestations of ER action; however, many new questions have emerged that make this area of research as exciting and interesting as it was 40 years ago." @default.
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- W1042196395 date "2004-01-01" @default.
- W1042196395 modified "2023-09-27" @default.
- W1042196395 title "Estrogens: From Classical Endocrine Action to Tissue Selective Action" @default.
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- W1042196395 doi "https://doi.org/10.1007/978-3-662-05386-7_1" @default.
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