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- W104902471 abstract "The formation of chromatin-associated poly(ADP-ribose) represents one of the earliest cellular reactions to DNA damage by physical and chemical carcinogens. Although the biological role of poly(ADP-ribose) formation is poorly understood, a large body of data is compatible with the idea that ADP-ribosylation acts to modify the biological expression of DNA damage during carcinogenesis [1]. As with other mechanisms whose functions become particularly obvious in the process of carcinogenesis, a biological role of polyADP-ribosylation reactions can also be demonstrated in normal cellular physiology and is generally related to the regulation of chromatin functions." @default.
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- W104902471 date "1985-01-01" @default.
- W104902471 modified "2023-09-26" @default.
- W104902471 title "ADP-Ribosylation, DNA Repair, and Chromatin Organization" @default.
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- W104902471 doi "https://doi.org/10.1007/978-3-642-70589-2_31" @default.
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